Table 1 Clinicopathologic characteristics of included studies
From: Surgical treatment to multiple primary lung cancer patients: a systematic review and meta-analysis
Study (Year) | Period | Country | Criteria | Type | Cases | Male (%) | Female (%) | Mean Age (years) | Smoker | Interval (months) | NOS Scale |
|---|---|---|---|---|---|---|---|---|---|---|---|
Van Rens (2000) [11] | 1970–1997 | Netherlands | M-M | SYN | 85 | 76 (89.4%) | 9 (10.6%) | 65.8 | NA | NA | 6 |
Doddoli (2001) [12] | 1985–1999 | France | M-M | MET | 38 | 35 (92%) | 3 (8%) | 63 ± 8 | 37 | 60 ± 51 | 6 |
Trousse (2007) [13] | 1985–2006 | France | defined | SYN | 125 | 98 (78.4%) | 27 (21.6%) | 61.5 ± 9.9 | 111 | NA | 7 |
De Leyn (2008) [14] | 1990–2007 | Belgium | defined | SYN | 36 | 29 (80.6%) | 7 (19.4%) | 64.5 | NA | NA | 7 |
Riquet (2008) [15] | 1993–2005 | France | M-M | Mixed | 234 SYN – 118 MET – 116 | 194 (82.9%) | 40 (17.1%) | 63.7 ± 9.1 | NA | NA | 6 |
Lee (2009) [16] | 1995–2008 | USA | defined | MET | 58 | 23 (39.7%) | 35 (60.3%) | 67 | NA | 42 | 6 |
Voltolini (2010) [17] | 1990–2007 | Italy | defined | SYN | 43 | 40 (93.0%) | 3 (7.0%) | 66.7 ± 6.9 | 40 | NA | 7 |
Hamaji (2013) [18] | 2000–2009 | USA | defined | MET | 161 | 88 (54.7%) | 73 (45.3%) | 70 | 138 | 42.7 | 7 |
Ishikawa (2014) [19] | 1995–2009 | Japan | Modified M-M | SYN | 93 | 36 (38.7%) | 57 (61.3%) | 68 | 33 | NA | 6 |
Xiao (2017) [20] | 2004–2015 | China | M-M | SYN | 52 | 36 (69.2%) | 16 (30.8%) | 60.3 ± 8.61 | 38 | NA | 7 |