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Table 1 Clinical and pathological characteristics of elderly patients with colorectal cancer before and after matching

From: Laparoscopic vs open colorectal cancer surgery in elderly patients: short- and long-term outcomes and predictors for overall and disease-free survival

Variables Total cohort Matched cohort
OPEN (n = 143) LAP (n = 170) P OPEN (n = 93) LAP (n = 93) P
Age (years, mean ± SD) (range) 82.3 ± 2.1 (80–92) 82 ± 2.1 (80–94) 0.280 82.1 ± 2.1 (80–92) 82.0 ± 2.2 (80–94) 0.814
Gender    0.445    0.655
 Male 91 (63.6%) 101 (59.4%)   56 (60.2%) 53 (57%)  
 Female 52 (36.4%) 69 (40.6%)   37 (39.8%) 40 (43%)  
BMI (kg/m2, mean ± SD) (range) 22.7 ± 3.3 (15.8–33.8) 23.7 ± 3.3 (15.6–34.1) 0.009 23.4 ± 3.0 (15.8–33.8) 23.2 ± 3.3 (16.8–34.1) 0.703
Preoperative HGB (g/L, mean ± SD) (range) 120.0 ± 19.1 (49–165) 124.5 ± 18.7 (62–161) 0.045 120.2 ± 19.6 (49–165) 121.5 ± 19.2 (62–161) 0.645
Preoperative albumin (g/L, mean ± SD) (range) 37.2 ± 4.3 (26.8–46.2) 40.2 ± 4.1 (29.1–46.8) < 0.001 38.4 ± 4.0 (29.5–46.2) 38.9 ± 4.0 (29.1–46.2) 0.409
ASA score    < 0.001    0.378
 I-II 52 (36.4%) 111 (65.3%)   47 (50.5%) 53 (57%)  
 III-IV 91 (63.6%) 59 (34.7%)   46 (49.5%) 40 (43%)  
Comorbidity    0.008    0.761
 Yes 83 (58.0%) 123 (72.4%)   60 (64.5%) 58 (62.4%)  
 No 60 (42.0%) 47 (27.6%)   33 (35.5%) 35 (37.6%)  
Previous abdominal surgery    0.456    0.721
 Yes 30 (21.0%) 30 (17.6%)   19 (20.4%) 21 (22.6%)  
 No 113 (79.0) 140 (82.4)   74 (79.6) 72 (77.4)  
Tumor location    0.007    0.698
 Right colon 51 (35.7%) 39 (23%)   32 (34.4%) 31 (33.3%)  
 Left colon 10 (6.9%) 4 (2.3%)   7 (7.5%) 4 (4.3%)  
 Sigmoid colon 31 (21.7%) 42 (24.7%)   21 (22.6%) 19 (20.4%)  
 Rectum 51 (35.7%) 85 (50%)   33 (35.5%) 39 (42%)  
Tumor differentiation    0.029    0.895
 Poor 29 (20.3%) 45 (26.5%)   23 (24.7%) 24 (25.8%)  
 Median 105 (73.4%) 123 (72.4%)   67 (72%) 67 (72%)  
 High 9 (6.3%) 2 (1.1%)   3 (3.3%) 2 (2.1%)  
TNM stage*    0.213    0.860
 I 8 (5.6%) 12 (7.1%)   8 (8.6%) 10 (10.8%)  
 II 45 (31.5%) 43 (25.3%)   30 (32.2%) 27 (29.0%)  
 III 83 (58.0%) 112 (65.8%)   53 (57.0%) 55 (59.1%)  
 IV 7 (4.9%) 3 (1.8%)   2 (2.2%) 1 (1.1%)  
Preoperative CEA (ng/mL)       0.503
 ≤ 5 102 (71.3%) 133 (78.2%) 0.159 67 (72%) 71 (76.3%)  
 > 5 41 (28.7%) 37 (21.8%)   26 (28%) 22 (23.7%)  
  1. OPEN open surgery; LAP laparoscopic surgery; BMI body mex index; HGB hemoglobin; ASA American Society of Anesthesiologists; TNM tumor nodes metastasis; CEA carcinoembryonic antigen; SD standard deviation; * evaluated based on 7th edition of AJCC