Table 1 Clinical and pathological characteristics of elderly patients with colorectal cancer before and after matching
Variables | Total cohort | Matched cohort | ||||
|---|---|---|---|---|---|---|
OPEN (n = 143) | LAP (n = 170) | P | OPEN (n = 93) | LAP (n = 93) | P | |
Age (years, mean ± SD) (range) | 82.3 ± 2.1 (80–92) | 82 ± 2.1 (80–94) | 0.280 | 82.1 ± 2.1 (80–92) | 82.0 ± 2.2 (80–94) | 0.814 |
Gender | 0.445 | 0.655 | ||||
Male | 91 (63.6%) | 101 (59.4%) | 56 (60.2%) | 53 (57%) | ||
Female | 52 (36.4%) | 69 (40.6%) | 37 (39.8%) | 40 (43%) | ||
BMI (kg/m2, mean ± SD) (range) | 22.7 ± 3.3 (15.8–33.8) | 23.7 ± 3.3 (15.6–34.1) | 0.009 | 23.4 ± 3.0 (15.8–33.8) | 23.2 ± 3.3 (16.8–34.1) | 0.703 |
Preoperative HGB (g/L, mean ± SD) (range) | 120.0 ± 19.1 (49–165) | 124.5 ± 18.7 (62–161) | 0.045 | 120.2 ± 19.6 (49–165) | 121.5 ± 19.2 (62–161) | 0.645 |
Preoperative albumin (g/L, mean ± SD) (range) | 37.2 ± 4.3 (26.8–46.2) | 40.2 ± 4.1 (29.1–46.8) | < 0.001 | 38.4 ± 4.0 (29.5–46.2) | 38.9 ± 4.0 (29.1–46.2) | 0.409 |
ASA score | < 0.001 | 0.378 | ||||
I-II | 52 (36.4%) | 111 (65.3%) | 47 (50.5%) | 53 (57%) | ||
III-IV | 91 (63.6%) | 59 (34.7%) | 46 (49.5%) | 40 (43%) | ||
Comorbidity | 0.008 | 0.761 | ||||
Yes | 83 (58.0%) | 123 (72.4%) | 60 (64.5%) | 58 (62.4%) | ||
No | 60 (42.0%) | 47 (27.6%) | 33 (35.5%) | 35 (37.6%) | ||
Previous abdominal surgery | 0.456 | 0.721 | ||||
Yes | 30 (21.0%) | 30 (17.6%) | 19 (20.4%) | 21 (22.6%) | ||
No | 113 (79.0) | 140 (82.4) | 74 (79.6) | 72 (77.4) | ||
Tumor location | 0.007 | 0.698 | ||||
Right colon | 51 (35.7%) | 39 (23%) | 32 (34.4%) | 31 (33.3%) | ||
Left colon | 10 (6.9%) | 4 (2.3%) | 7 (7.5%) | 4 (4.3%) | ||
Sigmoid colon | 31 (21.7%) | 42 (24.7%) | 21 (22.6%) | 19 (20.4%) | ||
Rectum | 51 (35.7%) | 85 (50%) | 33 (35.5%) | 39 (42%) | ||
Tumor differentiation | 0.029 | 0.895 | ||||
Poor | 29 (20.3%) | 45 (26.5%) | 23 (24.7%) | 24 (25.8%) | ||
Median | 105 (73.4%) | 123 (72.4%) | 67 (72%) | 67 (72%) | ||
High | 9 (6.3%) | 2 (1.1%) | 3 (3.3%) | 2 (2.1%) | ||
TNM stage* | 0.213 | 0.860 | ||||
I | 8 (5.6%) | 12 (7.1%) | 8 (8.6%) | 10 (10.8%) | ||
II | 45 (31.5%) | 43 (25.3%) | 30 (32.2%) | 27 (29.0%) | ||
III | 83 (58.0%) | 112 (65.8%) | 53 (57.0%) | 55 (59.1%) | ||
IV | 7 (4.9%) | 3 (1.8%) | 2 (2.2%) | 1 (1.1%) | ||
Preoperative CEA (ng/mL) | 0.503 | |||||
≤ 5 | 102 (71.3%) | 133 (78.2%) | 0.159 | 67 (72%) | 71 (76.3%) | |
> 5 | 41 (28.7%) | 37 (21.8%) | 26 (28%) | 22 (23.7%) | ||