Author, year

Country

No.

Location(D2)

Mitosis (/50HPF)

Risk category

Margins resection

Postoperative complication

Imatinib therapy

Median followup time


≥5

< 5

High/Intermediate

Low/Very low

R0

R1/R2


Gu [28], 2018

China

T: 62

T: 32

T: 10

T: 52

T: 28

T: 34

T: 61

T: 1

T: 11

T: 12

> 33 months

LR: 47

LR: 18

LR: 6

LR: 41

LR: 20

LR: 27

LR: 46

LR: 1

LR: 4

LR: 10

PD: 15

PD: 14

PD: 4

PD: 11

PD: 8

PD: 7

PD: 15

PD: 0

PD: 7

PD: 2

Lee, [21] 2018

South Korea

T: 98

T: 61

T: 25

T: 73

T: 35

T: 63

T: 95

T: 3

T: 32

T: 40

46 months

LR: 53

LR: NA

LR: 8

LR: 45

LR: 11

LR: 42

LR: 50

LR: 3

LR: 15

LR: NA

PD: 45

PD: NA

PD: 17

PD: 28

PD: 24

PD: 21

PD: 45

PD: 0

PD:17

PD: NA

Zhang, [22] 2018

China

T: 51

T: 33

T: 18

T: 30

T: 19

T: 32

T: 47

T: 4

T: 7

T: 23

36 months

LR: 37

LR: 24

LR: 13

LR: 21

LR: 12

LR: 25

LR: 33

LR: 4

LR: 4

LR: NA

PD: 14

PD: 9

PD: 5

PD: 9

PD: 7

PD: 7

PD: 14

PD: 0

PD: 3

PD: NA

Shi, [19] 2017

China

T: 61

T: 33

T: 10

T: 51

T: 24

T: 37

All R0

T: 24

T: 13

> 5 years

LR: 45

LR: 22

LR: 6

LR: 39

LR:15

LR:30

LR:15

LR: NA

PD: 16

PD: 11

PD: 4

PD: 12

PD:9

PD:7

PD:9

PD: NA

Chen, [23] 2017

China

T: 64

T: 30

T: 22

T: 42

T: 33

T: 31

All R0

T: 29

T: 15

> 5 years

LR: 41

LR: 18

LR: 12

LR: 29

LR: 17

LR: 24

LR: 13

LR: 8

PD: 23

PD: 12

PD: 10

PD: 13

PD: 16

PD: 7

PD: 16

PD: 7

Sugase, [20] 2016

Japan

T: 25

T: 14

NA

NA

T: 9

T: 16

All R0

T: 8

T: 3

> 5 years

LR: 16

LR: 7

LR: 3

LR: 13

LR: 5

LR: 1

PD: 9

PD: 7

PD: 6

PD: 3

PD: 3

PD: 2

Duffaud, [29] 2014

France

T: 105

T: 38

NA

NA

NA

NA

T: 85

T: 13

T: 21

T: 26

36 months

LR: 82

LR: NA

LR: 68

LR: 10

LR: 15

LR: NA

PD: 23

PD: NA

PD: 17

PD: 3

PD: 6

PD: NA

Zhou, [30] 2013

China

T: 48

T: 17

T: 12

T: 36

T: 20

T: 28

All R0

T: 9

T: 9

36 months

LR: 34

LR: 8

LR: NA

LR: NA

LR: 11

LR: 23

LR: 4

LR: NA

PD: 14

PD: 9

PD: NA

PD: NA

PD: 9

PD: 5

PD: 5

PD: NA

Colombo, [15] 2012

Italy,

T: 84

T: 21

T: 22

T: 56

T: 43

T: 41

T: 45

T: 9

T: 15

T: 34

42 months

LR: 56

LR: 6

LR: 11

LR: 41

LR: 24

LR: 32

LR: 26

LR: 9

LR: 5

LR: 19

PD: 28

PD: 15

PD: 11

PD: 15

PD: 19

PD: 9

PD: 19

PD: 0

PD: 10

PD:15

Tien, [31] 2010

China

T: 25

T: 13

T: 8

T: 17

T: 14

T: 11

T: 24

T: 1

T: 6

NOT

18 months

LR: 16

LR: 7

LR: 4

LR: 12

LR: 6

LR: 10

LR: 15

LR: 1

LR: 2

PD: 9

PD: 6

PD: 4

PD: 5

PD: 8

PD: 1

PD: 9

PD: 0

PD: 4

 LR Limited resection, PD Pancreaticoduodenectomy, T total, NA Not available, NOT No patients underwent imatinib therapy, D2 The second part of the duodenum, R0 Complete excision with all margins negative, R1 Incomplete excision with positive margins under microscopy, R2 Incomplete excision with macroscopic positive margins