Table 2 All cases of pancreatic mixed adenoneuroendocrine carcinoma involved in this study
No. | Reference | Age(year) | Sex | Presentation | Function | CA199 (U/ml) | Location | Treatment | Size (cm) | LN | Liver metastasis | Follow-up (month) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Eusebi (1981) [8] | 65 | M | Jaundice | NF | NA | H | PD | 6.0 | NA | Y | NA |
2 | Reid (1982) [9] | 29 | F | AP,WL,Jaundice | NF | NA | H | PD | NA | N | N | Alive (24) |
3 | Reid (1982) [9] | 50 | M | AP | NF | NA | H | DP | NA | Y | N | Alive (8) |
4 | Ordonez (1988) [10] | 62 | F | Diarrhea | VIPoma | NA | H | Chemo | 4.0 | NA | Y | Died (13) |
5 | Kashiwabara(1991) [11] | 48 | M | None | NF | Normal | H | PD | 1.9 | N | N | NA |
6 | Laine (1992) [12] | 59 | M | AP, Jaundice | NF | NA | H | PD | 6.0 | N | N | Alive (24) |
7 | Hassan (1993) [13] | 50 | M | AP,WL | NF | NA | D | DP | 19.0 | Y | N | Died (10) |
8 | Morikane (1997) [14] | 54 | F | None | Glucagonoma | Normal | D | DP | 1.0 | N | N | Alive (36) |
9 | Terada (1999) [15] | 62 | M | ZES | Hypergastrinemia | Normal | D | DP* | 1.0 | N | N | Died(288) |
10 | Leteurtre (2000) [16] | 74 | M | Jaundice, WL | NF | 127 | H | PD | 3.0 | Y | N | NA |
11 | Chatelain (2002) [17] | 72 | F | None | NF | NA | D | DP | 10.0 | N | N | Alive (4) |
12 | Terada (2002) [18] | 34 | M | AP | NF | Normal | D | DP | 0.5 | N | N | NA |
13 | Ballas (2005) [19] | 65 | F | AP, nausea | NF | NA | D | DP | 12.0 | N | N | Alive (18) |
14 | Hashimoto (2005) [20] | 75 | M | Jaundice | NF | 1289 | H | PD | 3.5 | N | N | Died (6) |
15 | Carter (2008) [21] | 58 | F | Jaundice | NF | NA | H | PD | 2.0 | Y | N | Alive (3) |
16 | Brandi (2008) [22] | 68 | M | AP | NF | Normal | D | DP | 4.0 | N | N | Died (12) |
17 | Araki(2011) [23] | 68 | M | None | NF | Normal | H | PD | 2.0 | N | N | Alive (52) |
18 | Murata(2017) [24] | 66 | M | Jaundice | NF | 95.6 | H | PD | 3.0 | Y | N | Died(12) |
19 | Xenaki(2016) [25] | 51 | M | AP, Jaundice | NF | Normal | H | PD | 1.5 | N | N | Died(13) |
20 | Kaji(2016) [26] | 60 | M | AP | NF | Normal | H | Chemo | 3.0 | NA | Y | Alive(18) |
21 | Imaoka(2016) [27] | 63 | M | None | NF | 51.1 | H | PD†| 2.0 | Y | N | Died(6) |
22 | The Present case | 65 | F | AP, Jaundice | NF | Normal | H | PD | 2.3 | Y | N | Died(15) |
23 | The Present case | 39 | F | AP | NF | 131 | H | PD | 2.3 | Y | Y | Died(32) |
24 | The Present case | 35 | F | AP | NF | 46.7 | D | DP‡ | 6.0 | N | N | Alive(36) |
25 | The Present case | 68 | M | None | NF | 74.4 | D | PD§ | 4.0 | Y | N | Died(6) |
26 | The Present case | 42 | F | AP, Jaundice | NF | 52.6 | H | PD†| 3.8 | Y | N | Alive(11) |
27 | The Present case | 48 | M | AP | NF | Normal | H | PD | 5.0 | N | N | Alive(5) |
28 | The Present case | 46 | M | AP, Back pain | NF | 2832 | D | Chemo | 3.0 | NA | N | Died(5) |
Total Results | Median age | M | AP | Functional | Elevated | H | PD | Median size | Y | Y | Median OS | |
59.5(29–75) | 64.3% | 53.6% | 89.3% | 32.1% | 64.3% | 57.1% | 3.0(0.5–19.0) | 35.7% | 14.3% | 12.5(3–288) |