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Table 2 Univariate Cox Regression of recurrence

From: Identifying risk factors of recurrence for clinically node negative papillary thyroid carcinoma with pathologic N1a

Variables

HR

95% CI

p

Age

  < 55 years

1

  

  ≥ 55 years

0.674

0.351–1.294

0.236

Sex

 Female

1

  

 Male

1.258

0.694–2.282

0.450

Tumor size

  ≤ 1 cm

1

  

  > 1 cm

1.656

1.006–2.725

0.047

Multifocality

 No

1

  

 Yes

1.543

0.929–2.562

0.094

Bilaterality

 No

1

  

 Yes

1.115

0.624–1.995

0.713

LVI

 No

1

  

 Yes

0.891

0.515–1.543

0.891

CLT

 No

1

  

 Yes

0.891

0.515–1.543

0.681

T stage

 T1/2/3a

1

  

 T3b

1.013

0.432–2.376

0.976

 T4a

4.019

2.079–7.773

< 0.001

ETE

 No gross ETE

1

  

 Gross ETE

1.964

1.124–3.433

0.018

Harvested LN

  ≤ 4

1

  

  ≥ 5

0.613

0.372–1.010

0.055

Positive LN

  ≤ 2

1

  

  ≥ 3

2.606

1.577–4.306

< 0.001

LN ratio

   

  ≤ 0.5

1

  

  > 0.5

4.992

2.791–8.928

< 0.001

TNM stage

 Stage I

1

  

 Stage II/III

0.507

0.184–1.398

0.189

  1. CI = Confidence interval, CLT = Chronic lymphocytic thyroiditis, ETE = Extrathyroidal extension, HR = Hazards ratio, LN = Lymph node, LVI = Lymphovascular invasion