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Table 1 Demographic and clinical data of reported cases of DSF after gastrectomy for malignant disease

From: Management of duodenal stump fistula after gastrectomy for malignant disease: a systematic review of the literature

Author/Year Study period Study type Patients with DSF, n Neoadjuvant chemotherapy, n AJCC TNM stage DSF diagnosis after operation, median days (range) DSF output, median ml/day (range) DSF-related complications
Garden et al./1988 [9] 1979–1985 RS 5 NA NA NA 1130 (120–2500)a NA
Bloch et al./1989 [10] 1989 Case 1 0 I 1 NA NA NA
Kyzer et al./1997 [11] 1991–1994 RS 2 NA NA NA NA Sepsis (50%)
Wong et al./2000 [12] 1993–1997 RS 1 NA NA NA 210 Abdominal abscess
Oh et al./2009 [13] 1987–2004 RS 5 NA NA NA NA Sepsis (100%)
Lee et al./2009 [14] 2009 Case 1 0 I 1 7 NA Abdominal abscess
Cozzaglio et al./2010 [5] 1991–2006 RS 68 2 NA 7 (0–22) 290 (40–2200) Abdominal abscess (38%), Wound infection (28%), Sepsis (26%), Central line infection (15%), Pneumonia (13%), Acute renal failure (10%), Colonic fistula (7%), Pancreatic fistula (6%), Acute pancreatitis (6%), Intraabdominal bleeding (6%), Abdominal wall necrosis (4%), Pulmonary embolism (3%), Jejunal fistula (3%), Roux-en-Y syndrome (3%), Esophagojejunal fistula (3%), Heart failure (3%), Others (11%)
Hur et al./2010 [15] 2005–2007 RS 4 NA NA NA NA Abdominal abscess (100%)
Cozzaglio et al./2011 [16] 2005–2010 RS 6 NA NA 6 (2–22) 500 (300–1000) Sepsis (50%)
Curcio et al./2012 [17] 2012 Case 1 0 I 1 NA NA Abdominal abscess
Oh et al./2013 [18] 2005–2011 RS 10 NA NA 10 (6–20) NA Abdominal fluids or abcess (100%)
Blouhos et al./2013 [19] 2013 Case 1 NA IV 1 1 NA Sepsis, Intra-abdominal bleeding
Vasiliadis et al./2014 [20] 2014 Case 1 NA III 1 NA NA Dehydration and electrolyte disorders
Kim et al./2014 [21] 2002–2012 RS 13 NA I 8, II 4, III 1 5 (1–12) NA NA
Orsenigo et al./2014 [3] 1987–2012 RS 32 0 I 7, II 9, III 9, IV 7 6.6 ± 4.7a 246 ± 266a Sepsis (75%), Abdominal abscess (69%), Pneumonia (34%), Surgical site infection (28%), Intra-abdominal bleeding (22%), Acute renal failure (16%), Colonic fistula (12%), Gastro-jejunal anastomosis leakage (6%), Central line infection (6%), Pneumothorax (6%)
Cornejo et al./2016 [22] 1997–2014 RS 13 NA I 4, II 5, III 2, IV 2 5 (3–7)a NA Sepsis (23%), Major Hematemesis (15%), Evisceration (8%), Abdominal abscess (8%)
Cozzaglio et al./2016 [4] 1990–2011 RS 75 3 NA 6 (2–11) 300 (100–750) Abdominal abscess (70.7%); Sepsis (61.3%); Pneumonia (44%); Surgical site infection (38.7%); Digestive fistulas (29.3%); 2Acute renal failure (28%); Intra-abdominal bleeding (24%); Central line infection (17.3%); Acute pancreatitis (9.3%); Abdominal wall necrosis (8%); Others (21.3%)
Ali et al./2016 [7] 2010–2014 RS 24 NA I 8, II 9, III 6, IV 1 8.5 (1–20) NA Pneumonia (20.8%), Sepsis (8.3%), Intra-abdominal bleeding (8.3%), Surgical site infection (8.3%), Deep vein thrombosis (8.3%)
Paik et al./2016 [6] 2008–2013 RS 16 NA NA 6.5 (1–13) NA NA
Ramos et al./2018 [2] 2009–2017 RS 15 2 I/II 9, III/IV 6 9 (1–75) NA NA
  1. amean, NA not available