Fig. 2

Case 23, a 65-y old female patient with metastatic tumor secondary to breast cancer. The bone strength score is 12. a, b The preoperative X-ray showed that the osteolytic destruction was located in the diaphysis of left humerus(S5 region). c, d The preoperative MRI indicated that the intramedullary destructive signals and soft-tissue swelling. e, f This patient underwent resection of the tumor and intercalary prosthetic reconstruction. g, h The proximal stem of the prosthesis occurred aseptic loosening 3 months after operation(arrow)