Effect of restrictive fluid therapy with hydroxyethyl starch during esophagectomy on postoperative outcomes: a retrospective cohort study

Table 3 Impact of intravenous fluid administered during esophageal surgery on composite outcomes

	Multivariable Adjusted
	Odds Ratio (95% CI)	P value
Crystalloid per weight (ml/kg)^a	1.008 (0.998–1.018)	0.101
HES per weight (ml/kg)^a	1.065 (1.043–1.088)	< 0.001
HES-to-crystalloid ratio^a	1.595 (1.191–2.136)	0.002
Total fluid per weight per hour (ml/kg/h)^a	1.178 (1.095–1.268)	< 0.001
HES-to-crystalloid ratio + total fluid^a
HES-to-crystalloid ratio	2.125 (1.521–2.969)	< 0.001
Total fluid per weight per hour (ml/kg/h)	1.248 (1.153–1.351)	< 0.001

^a: Adjusted by ASA class, preoperative hematocrit, preoperative use of diuretics, operation time, and pRBC transfused intraoperatively
CI = confidence interval; HES = hydroxyethyl starch; ASA = American Society of Anesthesiology; pRBC = packed red blood cell

ISSN: 1471-2482