Skip metastases to lateral cervical lymph nodes in differentiated thyroid cancer: a systematic review

BMC Surgery

Table 1 Studies published

Authors	Years	N° Patients	Type of Surgery TT+		Skip metastases	Tumor site		Tumor size		Capsular invasion
Authors	Years	N° Patients	CND	CND + LND	N°	Upper pole	Middle portion	< 10	> 10	Capsular invasion
Ducci M	1997	36	36	50 ispilateral 14 controlateral	11.1%	NE	NE	NE	NE	NE
Machens A	2004	215	215	95.3% ipsilateral 73.5% controlateral	13 (19.7%)	NS	NS	NS	NS	NS
Roh JL	2007	22	22	NS	3 (13,7%)	NE	NE	NE	NE	NE
Roh JL	2008	52	52	57	5	NS	NS	NS	NS	NS
Wada N	2008	231	231	231 ipsilateral	17	NS	NS	NS	NS	NS
Chung IS	2009	245	245	39 (12 metastases)	3
Xiao GZ	2010	121	121	121	9	NS	NS	NS	NS	NS
Park JH	2012	147	147	147	32 (21.8%)	NS	NS	32	NS	NS
Xiang D	2015	949	949	44	11	8	3	NS	NS	NS
Lei J	2017	450	450	450	39 (8.7%)	37 (94.9%)	2 (5.1%)	71.8%	NS	84.6%
Zhan X	2017	272	TT	NS	29 (10.7%)	95%	NS	95%	NS	NS
Xlin N	2017	203	203	203	30 (14.8%)	19
Lee B	2017	55	NS	55	3	NS	NS	NS	NS	NS

TT Total Thyroidectomy, CND central neck dissection, LND Lateral lymphoadenectomy, NE non evaluated, NS non specified

ISSN: 1471-2482