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Table 5 Uni- and multivariate analyses of risk factors for overall and recurrence-free survival in patients without synchronous metastases (n = 79)

From: Impact of postoperative complications on long-term survival following surgery for T4 colorectal cancer

Variable

Univariate P Value

Multivariate P Value

Hazard Ratio

(95% Confidence Interval)

Age ≥ 60 years

0.39

  

Male sex

0.28

  

BMI ≥ 30 kg/m2

0.79

  

ASA ≥ 2

0.03

0.03

4 (1–13)

Elevated CEA

0.17

  

Colon vs rectum

0.77

  

Synchronous metastases

–

  

Neoadjuvant treatment

0.17

  

Emergent surgery

0.55

  

Laparoscopic approach

0.96

  

Multiple organ resection

0.81

  

Synchronous liver resection

–

  

N+ status

0.03

0.01

4 (1–13)

R1 margins

0.05

0.02

3 (1–8)

Postoperative complications

0.90

  

Grade III-IV complications

0.82

  

Adjuvant chemotherapy

0.70

  
  1. Footnotes: BMI indicates body mass index, ASA American Score of Anesthesiologists, CEA carcinoembryonic antigen