Table 5 Reviewed papers for Sealants
From: A systematic review on the use of topical hemostats in trauma and emergency surgery
Year | Design | Comments | GoR-LoE | |
|---|---|---|---|---|
Allen et al. [49] | 2004 | Prospective randomized | Polymeric sealants may reduce air leak after pulmonary resection | 2A |
Belletrutti et al. [50] | 2008 | Retrospective | N-butyl-2-cyanoacrylate is effective and safe for bleeding control from gastric varices | 2A |
Coselli et al. [52] | 2003 | Prospective randomized | The bovine serum albumin and glutaraldehyde sealant is a safe and effective adjunct to reduce the occurrence of anastomotic site bleeding in cardiovascular surgery | 2A |
Dumville et al. [42] | 2014 | Cochrane review | There is some evidence that dehiscence rates may be higher in wound closed with tissue adhesives than with sutures; there was no evidence of any difference between sutures and tissue adhesive for outcomes such as cosmetic appearance and satisfaction | 1A |
Imkamp et al. [47] | 2015 | Prospective | Hemopatch® is effective to improve hemostasis in nephron-sparing surgery | 2B |
Kim et al. [45] | 2011 | Prospective randomized | Polyethylene glycol hydrogel spinal sealant is effective as adjunctive measure to improve watertight closure of dura mater in spine surgery | 2A |
Lewis et al. [43] | 2016 | Systematic review | Hemopatch® is an effective, easy-to-use hemostatic agent in open and minimally invasive surgery of patients with thrombin- or platelet-induced coagulopathies | 1C |
Miscusi et al. [53] | 2014 | Prospective | Sealants are useful for dural watertight closure | 2A |
Ollinger et al. [48] | 2013 | Prospective multicenter | Polyethylene glycol patch is useful in control of bleeding from hepatic cut surface | 2A |
Parildar et al. [51] | 2003 | Prospective | N-butyl cyanoacrylate is an useful tool for angioembolization of visceral psuedoaneurism | 2A |
Selli et al. [43] | 2013 | Case reports | N-butyl-2-cyanoacrylate represent a valid first line treatment to control urinary fistula when the output is not excessive and there is a favourable ratio between length and diameter of fistula tract | 2C |
Wright et al. [44] | 2015 | Prospective, randomized controlled, multicenter | Polyethylene glycol hydrogel sealant has been proven safe and effective for provide a watertight closure as an adjunct to sutured closure of durotomies | 2A |