From: A systematic review on the use of topical hemostats in trauma and emergency surgery
Year | Design | Comments | GoR-LoE | |
---|---|---|---|---|
Agarwal et al. [68] | 2010 | Case series | Excessive amount of oxidized cellulose may induce granuloma | 2C |
Broadbelt et al. [39] | 2002 | Case series | Excessive amount of cellulose in confined space like foramina may induce compression of spinal cord because of swelling | 2C |
Bruckner et al. [41] | 2014 | Retrospective | The use of polysaccharide hemospheres absorbable hemostat in complex cardiothoracic surgery resulted in significant reduction in hemostasis time, postoperative chest tube output, and need for postoperative blood transfusion | 2A |
Emmez et al. [38] | 2010 | Experimental in vivo | Microporous polysaccharides spheres may be used for hemostasis in neurosurgical setting, without inducing granuloma | 2A |
Lewis et al. [36] | 2013 | Experimental in vivo-in vitro preclinical | Oxidized non-regenerated cellulose provides superior hemostasis and equivalent bactericidal effectiveness relative to oxidized regenerated cellulose | 2C |
Menovsky et al. [69] | 2011 | Case reports | Removal of Surgicel® Fibrillar™ is advised after hemostasis has been achieved to avoid the development of complications due to a mass effect | 2C |
Ragusa et al. [34] | 2007 | Randomized prospective | Absorbable gelatin in association with antibiotic is effective in reduce bleeding and infectious complications after cardiac surgery | 2A |
Sabino et al. [37] | 2007 | Retrospective | 2B | |
Wagenhauser et al. [35] | 2016 | Experimental preclinical | Stronger inhibition of essential cellular processes of wound healing were observed for Oxidized non-regenerated cellulose when compared with oxidized regenerated cellulose | 2C |
Xu et al. [40] | 2016 | Randomized controlled | Hemostatic collagen sponge demonstrated better hemostasis effects than gelatin sponge with lower volume of postoperative drainage volume and blood loss in posterior spinal fusion | 2A |