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Table 4 Reviewed papers for mechanical hemostats

From: A systematic review on the use of topical hemostats in trauma and emergency surgery

 

Year

Design

Comments

GoR-LoE

Agarwal et al. [68]

2010

Case series

Excessive amount of oxidized cellulose may induce granuloma

2C

Broadbelt et al. [39]

2002

Case series

Excessive amount of cellulose in confined space like foramina may induce compression of spinal cord because of swelling

2C

Bruckner et al. [41]

2014

Retrospective

The use of polysaccharide hemospheres absorbable hemostat in complex cardiothoracic surgery resulted in significant reduction in hemostasis time, postoperative chest tube output, and need for postoperative blood transfusion

2A

Emmez et al. [38]

2010

Experimental in vivo

Microporous polysaccharides spheres may be used for hemostasis in neurosurgical setting, without inducing granuloma

2A

Lewis et al. [36]

2013

Experimental in vivo-in vitro preclinical

Oxidized non-regenerated cellulose provides superior hemostasis and equivalent bactericidal effectiveness relative to oxidized regenerated cellulose

2C

Menovsky et al. [69]

2011

Case reports

Removal of Surgicel® Fibrillar™ is advised after hemostasis has been achieved to avoid the development of complications due to a mass effect

2C

Ragusa et al. [34]

2007

Randomized prospective

Absorbable gelatin in association with antibiotic is effective in reduce bleeding and infectious complications after cardiac surgery

2A

Sabino et al. [37]

2007

Retrospective

 

2B

Wagenhauser et al. [35]

2016

Experimental preclinical

Stronger inhibition of essential cellular processes of wound healing were observed for Oxidized non-regenerated cellulose when compared with oxidized regenerated cellulose

2C

Xu et al. [40]

2016

Randomized controlled

Hemostatic collagen sponge demonstrated better hemostasis effects than gelatin sponge with lower volume of postoperative drainage volume and blood loss in posterior spinal fusion

2A