Skip to main content

Table 1 Descriptive statistics of the investigated cohort of 75 patients undergoing surgery for distal cholangiocarcinoma

From: Relevant prognostic factors influencing outcome of patients after surgical resection of distal cholangiocarcinoma

Variables

n (%)

Mean, Median (min.-max.)

Missing values n(%)

Age (years)

n.a.

65.2, 67 (33–87)

0 (0.0%)

Male gender

62 (82.7%)

n.a.

0 (0.0%)

Preoperative biliary stent

58 (77.3%)

n.a.

5 (6.7%)

Extent of surgery

Local bile duct excision w/o hilus

1 point

7 (9.3%)

3.0, 3 (1–5)

0 (0.0%)

Local bile duct excision with hilus

2 points

3 (4.0%)

Pancreaticoduodenectomy

3 points

54 (72.0%)

with hilus resection

4 points

5 (6.7%)

with portal vein resection

5 points

6 (8.0%)

Duration of operation (min)

n.a.

238.1, 230 (130–490)

0 (0.0%)

Grading

G1

1 point

2 (2.7%)

2.3, 2 (1–3)

0 (0.0%)

G2

2 points

51 (68.0%)

G3

3 points

22 (29.3%)

pT stages

pT1

1 point

4 (5.3%)

2.6, 3 (1–4)

0 (0.0%)

pT2

2 points

28 (37.3%)

pT3

3 points

36 (48%)

pT4

4 points

7 (9.3%)

pN stages

pN0

0 points

34 (45.3%)

0.6, 1 (0–2)

0 (0.0%)

pN1

1 point

39 (52%)

pN2

2 point

2 (2.7%)

M1 stage

5 (6.7%)

n.a.

0 (0.0%)

R0 resection

65 (86.7%)

n.a.

0 (0.0%)

Perineural invasion

46 (62.2%)

n.a.

1 (1.3%)

Venous invasion

16 (21.6%)

n.a.

1 (1.3%)

Lymph vessel invasion

22 (29.7%)

n.a.

1 (1.3%)

UICC stages

UICC Ia

1 point

4 (5.3%)

3.6, 4 (1–6)

0 (0.0%)

UICC Ib

2 points

15 (20.0%)

UICC IIa

3 points

9 (12.0%)

UICC IIb

4 points

32 (42.7%)

UICC III

5 points

9 (12.0%)

UICC IV

6 points

6 (8.0%)

Grading of complications

Clavien-Dindo Grade 0

0 points

25 (33.3%)

1.8, 1 (0–5)

2 (2.7%)

Clavien-Dindo Grade I

1 point

15 (20.0%)

Clavien-Dindo Grade II

2 points

7 (9.3%)

Clavien-Dindo Grade III

3 points

11 (14.7%)

Clavien-Dindo Grade IV

4 points

9 (12.0%)

Clavien-Dindo Grade V

5 points

6 (8.0%)

Complications leading to surgical intervention

19 (26.0%)

n.a.

2 (2.7%)

Observed overall survival in months

n.a.

29.1, 19 (0–145)

2 (2.7%)

Observed disease-free survival in months

n.a.

20.8, 13 (3–143)

47 (62.7%)

Hospital mortality

6 (8.0%)

n.a.

1 (1.3%)

Hospital stay in days

n.a.

29.8, 25 (7–102)

2 (2.7%)

ICU stay in days

n.a.

7.3, 3 (1–94)

17 (22.7%)

Days between onset of symptoms and date of surgery

n.a.

54.9, 34 (8–334)

36 (48.0%)

  1. Table 1: Shown are descriptive statistics of the investigated cohort of 75 patients. The extent of surgery was scaled from 1 (local bile duct excision without resection of the perihilar bile ducts) to 5 points (pancreaticoduodenectomy including partial portal vein resection). This scale was used to calculate the variable “extent of surgery graded in points multiplied by histological venous invasion” as displayed in Table 2