Table 3 Univariate analysis for factors predicting anastomotic leakage after TE

Age (years)

62.3 ± 7.8

57.8 ± 8.3

N.S.

Gender (Male, Female)

43, 15

14, 3

N.S.

BMI

21.3 ± 2.7

21.1 ± 2.8

N.S.

Preoperative chemotherapy

25 (43.1%)

9 (52.9%)

N.S.

TNM Stage (I, II, III, IV)

22, 13, 20, 3

6, 6, 4, 1

N.S.

Total operation time (min)

608 ± 112

594 ± 122

N.S.

Operation time of thoracic surgery (min)

338 ± 76

305 ± 60

N.S.

Blood loss (g)

380 (290–608)

350 (235–615)

N.S.

Blood Transfusion

6 (10.3%)

1 (5.9%)

N.S.

3-field lymph node dissection

15 (25.9%)

8 (47.1%)

N.S.

Paroxysmal atrial fibrillation

10 (17.2%)

3 (17.7%)

N.S.

Vasopressor agents

7 (12.1%)

1 (5.9%)

N.S.

WBC (10^3/μl) at 1POD

9.7 (8.2–12.8)

8.9 (7.0–11.5)

N.S.

CRP (10^4 μg/L) at 1POD

8.7 ± 2.4

10.5 ± 2.0

<  0.01

Lactic acid (mmol/L) at 1POD

1.5 (1.1–2.0)

2.0 (0.7–2.6)

N.S.

CPK (IU/L) at 1POD

919.5 (629–1400)

1232 (683–2177)

<  0.05

Postoperative hospital stay (days)

22 (19–28)

42 (30–47)

<  0.01