Skip to main content

Table 2 Multivariate analysis of risk factors associated with overall and disease-free survival

From: Survival after initial lung metastasectomy for metastatic colorectal cancer in the modern chemotherapeutic era

Variable (risk) HR [95% CI] P
Overall survival
General factor
  Sex (male) 2.262 [0.746–8.336] 0.153
Primary colorectal cancer related factors
  Location (rectum) 2.042 [0.698–6.344] 0.193
  N stage (N2) 1.422 [0.402–4.455] 0.566
Lung metastasis related factors
  Preoperative serum CEA (≥5.0 ng/mL) 3.793 [1.292–11.955] 0.015
  DFI after colorectal cancer resection (<24 months) 6.424 [1.708–42.585] 0.004
Disease-free survival
General factor
  Sex (male) 1.929 [0.893–4.352] 0.095
Primary colorectal cancer related factors
  N stage (N2) 3.106 [1.232–7.231] 0.018
  Vascular invasion (identified) 2.395 [0.769–10.536] 0.141
Lung metastasis related factors
  Tumor distribution (bilateral) 2.227 [0.720–6.147] 0.156
  Preoperative serum CEA (≥5.0 ng/mL) 1.977 [0.869–4.462] 0.103
  DFI after colorectal cancer resection (<24 months) 2.838 [1.271–7.224] 0.010
  1. CEA carcinoembryonic antigen, CI confidence interval, DFI disease-free interval, HR hazard ratio