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Table 1 Review of reported cases of isolated IgG4-associated cholangitis misdiagnosed as perihilar cholangiocarcinoma underwent surgical resections

From: Isolated IgG4-related sclerosing cholangitis misdiagnosed as malignancy in an area with endemic cholangiocarcinoma: a case report

Author/ Year

N

Sex

Age

Stricture location/Symptom

IgG4 (mg/dL)

Operation

Pathology

Hamano (2005) [34]

1

M

56

Perihilar, CBD/ Jaundice

1646

Hepatic resection with pancreaticoduodenectomy

Lymphoplasmacytic infiltration

IgG4-positive plasma cell infiltration

Cheung (2008) [35]

1

F

68

Perihilar/ Jaundice

2890

Hepatic resection

Lymphoplasmacytic sclerosing cholangitis

IgG4-positive plasma cells

Erdogan (2008) [11]

2

NA

NA

NA/ Jaundice

NA

Hepatic resection

Lymphoplasmacytic infiltration

Moderate IgG4-positive plasma cells

Fujita (2010) [12]

1

M

60

Perihilar/ Jaundice

NA

Bile duct resection

Lymphoplasmacytic infiltration

Diffuse IgG4-positive plasma cells

Lytras (2012) [13]

1

NA

NA

NA/ NA

Negative

Hepatic resection

Class A (HISORt criteria)

Nguyen-tat (2012) [36]

1

M

79

Perihilar/ Jaundice

40

Hepatic resection with bile duct resection

Lymphoplasmacytic infiltration

IgG4-positive plasma cells > 50 cells/HPF

Matusubayashi (2014) [37]

1

M

70

Perihilar/ Jaundice

1.10

Hepatic resection with bile duct resection

Lymphoplasmacytic infiltration

IgG4-positive cells 10 cells/HPF

Zaydfudim (2015) [38]

2

M

M

68

79

Perihilar/ abdominal pain

Perihilar/ abnormal LFT

61.3

39.4

Hepatic resection with bile duct resection

Hepatic resection with bile duct resection

Lymphoplasmacytic infiltration

IgG4-positive plasma cells > 40%

IgG4-positive plasma cells >50 cells/HPF

Miki (2015) [39]

1

M

69

Perihilar/ Jaundice

381

Bile duct resection

Lymphocyte and plasma cell infiltration

IgG4-positive plasma cells > 50 cells/HPF

Ignjatovic (2015) [40]

1

M

60

Perihilar, CBD/ Jaundice, abdominal pain

80

Bile duct resection

Dense fibro-inflammatory infiltration with lymphoid cells

IgG4-positive plasmacytoid cells

Lin (2015) [41]

4

M

M

M

M

84

70

72

61

Perihilar/ Jaundice

NA

Bile duct resection

Lymphoplasmacytic infiltration

IgG4-positive cells >50 cells/HPF

Present study

1

M

56

Perihilar/ Jaundice

>7230

Hepatic resection with bile duct resection

Lymphoid and plasma cell infiltration

IgG4-positive plasma cells 80 cells/HPF

  1. M male, F female, CBD common bile duct, LFT liver function test, HPF high-power field