Prognostic value of preoperative inflammatory response biomarkers in patients with esophageal cancer who undergo a curative thoracoscopic esophagectomy

Table 4 Univariate and multivariate analysis of prognostic factors in 101 non-elderly patients with esophageal cancer

Variables	Patients (n = 101)	Category or characteristics	Univariate			Multivariate
Variables	Patients (n = 101)	Category or characteristics	HR	95 % CI	p value	HR	95 % CI	p value
Gender	10/91	(female/male)	0.608	0.233–20.78	0.388
pStage	61/40	(1,2/3)	5.022	2.321–11.715	<0.0001	4.009	1.731–10.162	0.001
Tumor size	34/67	(3</≥3)	8.34	2.491–51.782	0.0001	3.115	0.788–20.674	0.1114
Operation time	67/34	(600</≥600)	2.219	1.048–4.752	0.0374	1.109	0.490–2.540	0.803
Intraoperative blood loss	49/52	(500</≥500)	1.53	0.723–3.373	0.2679
LMR	58/43	(≥4/4<)	5.076	2.259–12.909	<0.0001	4.553	1.856–12.516	0.0007
NLR	25/76	(≥1.6/1.6<)	1.593	0.656–4.750	0.322
PLR	54/47	(147</≥147)	2.475	1.160–5.592	0.0189	1.163	0.499–2.845	0.5999
SCC antigen	76/25	(1.5</≥1.5)	0.915	0.305–2.244	0.857

LMR lymphocyte to monocyte ratio, NLR neutrophil to lymphocyte ratio, PLR platelet lymphocyte ratio, SCC squamous cell carcinoma, HR hazard ratio, CI confidence interval

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