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Table 3 Primary liver diseases and presumptive causes of AKI after operation according to in-hospital mortality

From: Proteinuria can predict prognosis after liver transplantation

 

All patients

Survivors

Non-survivors

P-value

n = 323

n = 281

n = 42

Primary liver disease

323 (100)

281 (100)

42 (100)

 

 Alcoholic, n (%)

16 (5)

12 (4)

4 (10)

NS (0.254)

 Hepatitis B, n (%)

111 (34)

100 (36)

11 (26)

NS (0.848)

 Hepatitis C, n (%)

31 (10)

23 (8)

8 (19)

0.003

 Hepatoma, n (%)

3 (1)

3 (1)

0 (0)

NS (1.000)

 Alcoholic + hepatitis B, n (%)

21 (6)

15 (7)

2 (5)

NS (1.000)

 Alcoholic + hepatitis C, n (%)

5 (2)

5 (2)

0 (0)

NS (1.000)

 Alcoholic + hepatoma, n (%)

3 (1)

3 (1)

0 (0)

NS (1.000)

 Hepatitis B + hepatitis C, n (%)

17 (5)

14 (5)

3 (7)

NS (0.723)

 Hepatitis B + hepatoma, n (%)

49 (15)

43 (15)

6 (14)

NS (0.172)

 Hepatitis C + hepatoma, n (%)

31 (10)

29 (10)

2 (5)

NS (0.134)

 Alcoholic + hepatitis B + hepatoma, n (%)

2 (1)

1 (1)

1 (2)

NS (0.429)

 Other causes, n (%)a

34 (10)

29 (10)

5 (12)

NS (0.787)

Presence of AKI after transplantation (Post-OP day1)

125 (39)

101 (36)

24 (57)

0.011

 Prerenal type of AKI, n (%)

2 (1)

2 (1)

0 (0)

NS (1.000)

 Infection related AKI, n (%)

42 (13)

31 (11)

11 (26)

0.006

 Nephrotoxic agent exposure related AKI, n (%)

6 (2)

6 (2)

0 (0)

NS (0.601)

 Mixed type and other causes of AKI, n (%)b

75 (23)

62 (22)

13 (31)

NS (0.236)

  1. Values in bold are statistically significant (P-value < 0.05)
  2. Hepatitis C virus infection was independently associated with in-hospital mortality
  3. Presence of infection related AKI on the first day after transplantation was independently associated with in-hospital mortality
  4. aBiliary cirrhosis, biliary sclerosis, autoimmune hepatitis, Wilson’s disease, polycystic liver disease, drugs, and unknown causes
  5. bMultifactor related, ischemia/reperfusion injury, or unknown cause