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Table 2 Patient demographic data and clinical characteristics according to in-hospital mortality

From: Proteinuria can predict prognosis after liver transplantation

 

All patients (n = 323)

Survivors (n = 281)

Non-survivors (n = 42)

P-value

Age (years)

50.8 ± 10.4

50.9 ± 9.8

50.3 ± 13.8

NS (0.753)

Gender (M/F)

231/92

199/82

32/10

NS (0.583)

BMI on admission (kg/m2)

24.3 ± 4.0

24.7 ± 4.0

21.1 ± 2.4

<0.001

History of diabetes mellitus (yes/no)

55/268

46/235

9/33

NS (0.387)

History of chronic kidney disease (yes/no)

31/292

22/259

9/33

0.005

Proteinuria on admission (yes/no)

45/278

31/250

14/28

<0.001

Hemoglobin on admission (g/dL)

10.6 ± 2.2

10.7 ± 2.2

9.8 ± 2.1

0.008

Leukocytes on admission (× 109/L)

2.9 ± 3.7

2.8 ± 3.5

3.3 ± 4.9

NS (0.569)

Platelets on admission (× 109/L) [median]

72.7 [60]

72.9 ± [60]

71.1 [59]

NS (0.809)

Prothrombin time INR on admission

1.8 ± 0.7

1.8 ± 0.7

1.9 ± 0.7

NS (0.050)

Serum sodium on admission (mmol/L)

137.8 ± 5.7

137.9 ± 5.4

137.0 ± 8.0

NS (0.471)

AST on admission (U/L) [median]

88.8 [62]

87.5 [64]

98.3 [51]

NS (0.498)

ALT on admission (U/L) [median]

67.2 [39]

67.4 [40]

65.8 [34]

NS (0.938)

Total bilirubin on admission (μmol/L) [median]

145.4 [51]

130.0 [50]

244.5 [96]

0.003

A-a gradient on admission (mmHg) [median]

25.1 [17]

22.8 [17]

43.3 [18]

0.039

Serum creatinine on admission (μmol/L) [median]

97.2 [77]

92.2 [75]

114.9 [84]

NS (0.064)

Hepatorenal syndrome, n (%)

29 (9)

22 (8)

7 (17)

NS (0.079)

MAP on admission (mmHg)

86.1 ± 12.4

86.3 ± 12.7

84.7 ± 10.3

NS (0.427)

Child-Pugh points on admission

10.1 ± 2.6

9.9 ± 2.7

11.1 ± 2.0

0.010

MELD score on admission

17.6 ± 9.0

17.1 ± 8.9

21.4 ± 9.7

0.025

RIFLE on admission (No AKI/Risk/Injury/Failure)

286/16/9/12

250/13/9/9

36/3/0/3

NS (0.449)

SOFA score on admission

5.1 ± 2.7

4.8 ± 2.5

6.7 ± 3.3

0.001

Anesthesia time during operation (hours)

12.1 ± 1.8

12.1 ± 1.9

12.4 ± 1.5

NS (0.362)

Donor type (DDLT /LDLT)

91/232

74/207

17/25

0.018

Total operative time (mins) [median]

687.1 [683]

685.6 [683]

697.2 [682]

NS (0.589)

Cold ischemia time (mins) [median]

85.0 [15]

74.8 [15]

166.4 [17]

NS (0.125)

Warm ischemia time (mins) [median]

128.2 [122]

126.3 [121]

141.1 [129]

NS (0.115)

Graft-to-recipient weight ratio (%)

1.0 ± 0.3

1.0 ± 0.3

1.1 ± 0.5

NS (0.125)

Blood loss volume during operation (ml) [median]

3034 [2000]

2672 [1840]

4430 [2000]

0.014

Length of ICU stay (days) [median]

21.0 [14]

19.2 [14]

33.6 [24]

0.002

Length of hospital stay (days) [median]

47.8 [38]

46.7 [38]

54.7 [44]

NS (0.215)

  1. Values in bold are statistically significant (P-value < 0.05)
  2. There were significant differences in BMI on admission, history of chronic kidney disease, presence of proteinuria on admission, hemoglobin on admission, total bilirubin on admission, A-a gradient on admission, Child-Pugh points on admission, MELD score on admission, SOFA score on admission, blood loss volume during operation, and length of ICU stay
  3. Abbreviation: M male, F female, ICU intensive care unit, MAP mean arterial pressure, INR international normalized ratio, AST aspartate aminotransferase, ALT alanine aminotransferase, DM diabetes mellitus, MELD model for end-stage liver disease, SOFA sequential organ failure assessment, AKI acute kidney injury, DDLT deceased donor liver transplantation, LDLT living donor liver transplantation