Table 2 Operative and perioperative details at time of liver-directed therapy of our study population (n = 35 patients) according to state of Tyrosinkinase Inhibitor (TKI) Therapy

 Minor resection

17 (51.5 %)

11 (33.3 %)

6 (18.2 %)

0.008^d

 Major

16 (48.5 %)

3 (9.1 %)

13 (39.4 %)

 Segmental resection

9 (27.3 %)

6 (18.2 %)

3 (9.1 %)

0.13^d

 Anatomical right/left resection

11 (33.3 %)

9 (27.2 %)

2 (6.1 %)

0.003^d

 Extended resection right/left

5 (15.2 %)

4 (12.1 %)

1 (3.1 %)

0.06^d

 Atypical resection

8 (24.2 %)

4 (12.1 %)

4 (12.1 %)

0.61^d

 Complete Resection (R0)

30 (85.7 %)

14 (40 %)

16 (45.7 %)

0.78^d

 Microscopically positive margin (R1)

5 (14.3 %)

2 (5.7 %)

3 (8.6 %)

 Substitution

15 (8 %)

9 (4.8 %)

3 (1.6 %)

0.7^d

  - Transfusion erythrocyte concentrations

0.27 (0–6)

0.23 (0–6)

0.36 (0–4)

0.7^d

  - Transfusion Fresh frozen plasma

0.17 (0–8)

0.2 (0–8)

0.03 (0–1)

0.7^d

 Pringle manoeuvre

19 (54.3 %)

6 (17.1 %)

13 (37.1 %)

0.067^c

 Median Hospital stay (days)

18.7 (11–28)

16.6 (11–18)

20.5 (16–24)

0.360^a

 Median Intensive care unit stay (days)

1.9 (1–6)

2.0 (1–6)

1.8 (1–5)

0.716^a

 Median Operating time (min)

238 (161.5–276)

224.5 (164.5–272.5)

242 (155–281)

0.477^a

 Grade I

0 (0 %)

0 (0 %)

0 (0 %)

-

 Grade II

3 (8.6 %)

2 (5.7 %)

1 (2.9 %)

0.434^d

 Grade IIIa

5 (14.3 %)

4 (11.4 %)

1 (2.9 %)

0.096^d

 Grade IIIb

1 (2.9 %)

0 (0 %)

1 (2.9 %)

0.352^d

 Grade Iva

1 (2.9 %)

1 (2.9 %)

0 (0 %)

0.269^d

 Grade IVb

0 (0 %)

0 (0 %)

0 (0 %)

-

 Grade V

0 (0.5 %)

0 (0 %)

0 (0 %)

-