Fig. 1From: A randomized controlled trial to compare a restrictive strategy to usual care for the effectiveness of cholecystectomy in patients with symptomatic gallstones (SECURE trial protocol)Flow-chart of the inclusion, randomization and management in the SECURE-trial. *Bilairy colic symtoms are defined as severe steady pain, lasting 15–30 min or longer, usually located in the epigastrium and/or right upper quadrantBack to article page