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Table 2 Factors influencing disease-free survival (DFS) for patients with Barcelona Clinic Liver Cancer stage B hepatocellular carcinoma after R0 resection

From: Combined measurements of tumor number and size helps estimate the outcome of resection of Barcelona clinic liver cancer stage B hepatocellular carcinoma

Factors

Kaplan–Meier analysis

Cox regression hazard model

Median DFS (mo)

P value

HR(95 % CI)

P value

Sex (male/female)

15.0/13.0

0.771

  

Age (≤60/>60 years)

15.0/13.0

0.530

  

Alcohol consumption (no/yes)a

15.0/18.0

0.463

  

Preoperative TACE (no/yes)

13.0/33.0

0.058

  

HBsAg (negative/positive)

8.0/18.0

0.267

  

Anti-HCV (negative/positive)

15.0/11.4

0.529

  

ALT (≤50/>50 U/L)

23.0/11.4

0.076

  

GGT (≤64/>64 U/L)

19.0/13.0

0.096

  

Child–Pugh classification (A/B)

15.0/5.7

0.288

  

Cirrhosis (no/yes)

25.0/15.0

0.317

  

Portal hypertension (no/yes)

15.0/23.0

0.769

  

Liver resection range (≤2/>2 segments)

17.0/8.0

0.084

  

Resection margin (<5/≥5 mm)a

13.0/19.0

0.573

  

Anatomical resection (yes/no)

14.6/15.0

0.783

  

Hepatic inflow occlusion (no/yes)

13.0/19.0

0.223

  

Intraoperative blood loss (≤1000/>100 mL)

18.0/13.0

0.282

  

Blood transfusion (yes/no)

17.0/15.0

0.732

  

Preoperative alpha-fetoprotein (≤20/>20 μg/L)

14.6/18.0

0.273

  

Cumulative tumor size (≤5/>5 cm)

25.0/13.0

0.009

1.685 (1.011–2.808)

0.045

Tumor number (≤3/≥4)

23.0/10.1

0.000

2.681 (1.506–4.770)

0.001

Differentiation (high/middle and low/necrosis)

24.0/15.0/19.2

0.671

  

Liver capsule invasion (no/yes)

13.0/17.0

0.882

  
  1. aSome patients lacked data