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Table 2 Univariate analysis and logistic regression analysis correlations between the number of harvested lymph nodes (12 LNs examined in the high-harvest group or < 12 LNs examined in the low-harvest group) and other variables among 797 stage I-III colon cancer patients

From: Factors affecting number of lymph nodes harvested and the impact of examining a minimum of 12 lymph nodes in stage I-III colorectal cancer patients: a retrospective single institution cohort study of 1167 consecutive patients

  Low-harvest group High-harvest group Univariate analysis Logistic regression analysis
Variables (n = 197) (%) (n = 600) (%) P-value ORa (95 % CIb) P-value
Gender     
 Male/Female 115 (58.4)/82 (41.6) 339 (56.5)/261 (43.5) 0.645 - -
Age (y/o)     
65/<65 120 (60.9)/77 (39.1) 295 (49.2)/305 (50.8) 0.004 1.582 (1.131–2.212) 0.007
Tumor size (cm)     
  < 5/5 140 (71.1)/57 (28.9) 347 (57.8)/253 (42.2) 0.001 1.503 (1.040–2.171) 0.030
Depth of invasion     
 T1 + T2/T3 + T4 81 (41.2)/116 (58.8) 134 (22.4)/466 (77.6) <0.0001 1.919 (1.318–2.795) 0.001
TNM stage     
 I + II/III 141 (71.6)/56 (28.4) 350 (58.3)/250 (41.7) 0.001 1.427 (0.984–2.070) 0.061
Tumor histology     
 M + S/Ac 13 (6.6)/184 (93.4) 39 (6.5)/561 (93.5) 0.961 - -
Tumor grade     
 WD + MD/PDd 181 (91.8)/16 (8.2) 539 (89.8)/61 (10.2) 0.399 - -
Vascular invasion     
 Yes/No 46 (23.4)/151 (76.6) 131 (21.8)/469 (78.2) 0.657 - -
Perineural invasion     
 Yes/No 49 (24.9)/148 (75.1) 146 (24.4)/454 (75.6) 0.878 - -
Type of surgery     
 Laparoscopic/Open 38 (19.3)/159 (80.7) 101 (16.8)/499 (83.2) 0.431 - -
Preoperative CEAe (ng/ml)     
5/<5 68 (34.5)/129 (65.5) 217 (36.2)/383 (63.8) 0.675 - -
  1. a OR odds ratio
  2. b95 % CI 95 % confidence interval
  3. c M mucinous carcinoma, S signet-ring cell carcinoma, A adenocarcinoma
  4. d PD poorly differentiated, MD moderately differentiated, WD well differentiated
  5. e CEA carcinoembryonic antigen