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Table 2 Univariate analysis and logistic regression analysis correlations between the number of harvested lymph nodes (12 LNs examined in the high-harvest group or < 12 LNs examined in the low-harvest group) and other variables among 797 stage I-III colon cancer patients

From: Factors affecting number of lymph nodes harvested and the impact of examining a minimum of 12 lymph nodes in stage I-III colorectal cancer patients: a retrospective single institution cohort study of 1167 consecutive patients

 

Low-harvest group

High-harvest group

Univariate analysis

Logistic regression analysis

Variables

(n = 197) (%)

(n = 600) (%)

P-value

ORa (95 % CIb) P-value

Gender

    

 Male/Female

115 (58.4)/82 (41.6)

339 (56.5)/261 (43.5)

0.645

- -

Age (y/o)

    

65/<65

120 (60.9)/77 (39.1)

295 (49.2)/305 (50.8)

0.004

1.582 (1.131–2.212) 0.007

Tumor size (cm)

    

  < 5/5

140 (71.1)/57 (28.9)

347 (57.8)/253 (42.2)

0.001

1.503 (1.040–2.171) 0.030

Depth of invasion

    

 T1 + T2/T3 + T4

81 (41.2)/116 (58.8)

134 (22.4)/466 (77.6)

<0.0001

1.919 (1.318–2.795) 0.001

TNM stage

    

 I + II/III

141 (71.6)/56 (28.4)

350 (58.3)/250 (41.7)

0.001

1.427 (0.984–2.070) 0.061

Tumor histology

    

 M + S/Ac

13 (6.6)/184 (93.4)

39 (6.5)/561 (93.5)

0.961

- -

Tumor grade

    

 WD + MD/PDd

181 (91.8)/16 (8.2)

539 (89.8)/61 (10.2)

0.399

- -

Vascular invasion

    

 Yes/No

46 (23.4)/151 (76.6)

131 (21.8)/469 (78.2)

0.657

- -

Perineural invasion

    

 Yes/No

49 (24.9)/148 (75.1)

146 (24.4)/454 (75.6)

0.878

- -

Type of surgery

    

 Laparoscopic/Open

38 (19.3)/159 (80.7)

101 (16.8)/499 (83.2)

0.431

- -

Preoperative CEAe (ng/ml)

    

5/<5

68 (34.5)/129 (65.5)

217 (36.2)/383 (63.8)

0.675

- -

  1. a OR odds ratio
  2. b95 % CI 95 % confidence interval
  3. c M mucinous carcinoma, S signet-ring cell carcinoma, A adenocarcinoma
  4. d PD poorly differentiated, MD moderately differentiated, WD well differentiated
  5. e CEA carcinoembryonic antigen