Long-term prognosis after resection of cryptogenic hepatocellular carcinoma

BMC Surgery

Table 3 Results of univariate and multivariate analysis of the predictors for overall survival in CR-HCC, B-HCC, and C-HCC

Variables	Category	P(uni)	P(multi)	Multi hazard ratio
CR-HCC
Number of tumors	Single/multiple	0.062	0.024	3.9 (1.2–12.8)
Intraoperative RBC transfusion	Yes/no	0.004	0.095	4.0 (0.79–20.3)
Degree of differentiation of the main tumor	well, moderate/poorly	0.019	0.001	8.5 (2.3–31.3)
Tumor size	<50/≧50 mm	0.040	0.042	5.3 (1.1–26.0)
LC	Yes/no	0.068
Platelet count	<10 × 10⁴/≧10 × 10⁴ /ml	0.004	<0.001	9.6 (2.7–34.3)
B-HCC
Number of tumors	Single/multiple	0.055
Intraoperative RBC transfusion	Yes/no	0.004	<0.001	13.4 (4.7–38.1)
Degree of differentiation of the main tumor	well, moderate/poorly	0.007	0.003	2.7 (1.4–5.2)
Tumor size	<50/≧50 mm	0.004
LC	Yes/no	0.041
ICGR15	<15/≧15 %	<0.001	<0.001	3.5 (1.8–6.8)
C-HCC
Gender	Male/Female	0.626	0.012	1.6 (1.1–2.4)
Number of tumors	Single/multiple	0.101
Intraoperative RBC transfusion	Yes/no	<0.001	0.016	1.9 (1.1–3.1)
Cancer spread	Yes/no	0.003	0.002	1.7 (1.2–2.3)
LC	Yes/no	<0.001	<0.001	2.1 (1.5–3.0)
ICGR15	<15/≧15 %	<0.001	0.003	1.9 (1.2–2.8)
Platelet count	<10 × 10⁴/≧10 × 10⁴ /ml	0.001
AFP	<100/≧100 AU/l	0.005	0.018	1.5 (1.1–2.1)

CR-HCC cryptogenic hepatocellular carcinoma, B-HCC hepatitis virus B-related hepatocellular carcinoma, C-HCC hepatitis virus C-related hepatocellular carcinoma, AFP alpha-fetoprotein, DCP des-r-carboxyprothrombin, ICGR15 indocyanine green retention rate at 15 min, LC Liver cirrhosis

ISSN: 1471-2482