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Table 4 Survival analysis for 89 Patients With pT1 Ampullary Cancer

From: Long-term prognosis of surgical treatment for early ampullary cancers and implications for local ampullectomy

  Univariate analysis Multivariate analysis
  5-year survival rate 10-year survival rate P HR (95%CI)  
Age    0.756 ______  
  <65 69.0% 44.1%    
  ≥65 67.0% 41.0%    
Gender    0.880 ______  
  Female 69.3% 43.3%    
  Male 67.1% 40.6%    
Jaundice    0.683 ______  
  Positive 59.1% 39.8%    
  Negative 68.3% 49.1%    
Gross morphology    0.006 1 2.536 (1.351-4.860) 0.004
  Polypoid 75.8% 48.0%    
  Ulcerative 44.2% 29.5%    
Tumor size    0.016 1 2.204 (1.171-4.148) 0.014
  ≤1 cm 78.8% 50.9%    
  >1 cm 54.7% 37.7%    
Tumor grade    0.017 1 4.213 (1.868-9.504) 0.001
  Well 88.1% 61.1%    
  Moderate/poor 56.8% 34.6%    
Lymph node metastasis    <0.001 1 4.362 (2.126-8.952) <0.001
  Negative 74.4% 49.4%    
  Positive 32.1% 0.0%    
Lymphovascular invasion    <0.001   <0.001
  Negative 69.4% 51.l%   1  
  Positive 33.2% 12.1%   4.258 (2.013-8.861)  
Perineural invasion    <0.001   <0.001
  Negative 72.1% 45.6%   1  
  Positive 36.8% 15.3%   4.467 (2.315-9.034)  
Operation style    0.639   0.549
Pancreaticoduodenectomy 65.6% 38.7%   1  
Local ampullectomy 64.6% 42.6%   1.372 (0.854-1.762)