Table 6 Surgeon and technical factors associated with nodal mapping, identification and pathological analysis methodology.
| Â | Â | Â | Â | Â | Â | Â | Sentinel node analysis | |
|---|---|---|---|---|---|---|---|---|
Lead Author | Surgeon Experience sought | Multicentre | Laparoscopic resection (%) | Mapping agent used | Supplementay ex vivo identification | Mean/median No. of sentinel nodes (range) | Serial sectioning | Immunohist. or RT-PCR |
Saha | No | No | ns | Isosulfan blue 1% | No | 1.6 (1 to 4) | Yes | No |
Wiese | No | No | 0 | Isosulfan blue 1% | No | 1.9 (1 to 4) | Yes | Yes |
Waters | No | No | ns | Isosulfan blue 1% | No | ns | Yes | Yes |
Bilchik | Yes | Yes | ns | Isosulfan blue 1% | No | 2 (1 to 3) | Yes | Yes |
Paramo | No | No | 0 | Isosulfan blue 1% | No | 1.4 (1 to 4) | Yes | Yes |
Wood | No | No | 12 | Isosulfan blue 1% | Yes (10%) | 2 (1 to 4) | Yes | Yes |
Wood | No | No | 100 | Isosulfan blue 1% | No | 2 (1 to 3) | Yes | Yes |
Saha | No | Yes | ns | Isosulfan blue 1% | No | 1.7 (1 to 4) | Yes | Yes |
Esser | No | No | 0 | Isosulfan blue 1% | No | 1.7 (0 to 5) | No | No |
Bendavid | No | No | ns | Isosulfan blue 1% | No | 3.9 (0 to 5) | Yes | Yes |
Paramo | No | No | 0 | Isosulfan blue 1% | No | 1.6 (0 to 4) | Yes | Yes |
Wood | No | No | ns | Isosulfan blue 1% | Yes (15%) | 2 (1 to 4) | Yes | Yes |
Bilchik | No | No | 16 | Isosulfan blue 1% | Yes (11%) | 2 (1 to 4) | Yes | Yes |
Kitagawa | No | No | 0 | Techneticum | No | 3.5 (0 to 8) | No | No |
Feig | No | Yes | 0 | Isosulfan blue 1% | No | 2.6 (0 to 7) | No | Yes |
Broderick-Villa | No | No | 0 | Isosulfan blue 1% | Yes (23%) | 1.5 (0 to 5) | Yes | Yes |
Tsioulias | No | No | 100 | Isosulfan blue 1% | No | 1.7 (1 to 3) | Yes | Yes |
Nastro | No | No | 0 | Technetium and blue dye | No | ns | Yes | Yes |
Bilchik | Yes | No | 23 | Isosulfan blue 1% | No | 2 (1 to 3) | Yes | Yes |
Cox | No | No | 0 | Isosulfan blue 1% | Yes (58%) | 6 (2 to 11) | Yes | Yes |
Bilchik | Yes | No | ns | Isosulfan blue 1% | No | 1.75 (ns) | Yes | Yes |
Turner | Yes | No | ns | Isosulfan blue 1% | No | 3 (ns) | Yes | Yes |
Trocha | No | No | 0 | Technetium and blue dye | No | 2.5 (ns) | Yes | Yes |
Veihl | No | Yes | 0 | Isosulfan blue 1% | No | 2 (1 to 8) | Yes | Yes |
Levine | No | No | 0 | Isosulfan blue 1% | No | 1.9 (1 to 6) | No | Yes |
Saha | Yes | No | ns | Isosulfan blue 1% | No | 2.1 (ns) | Yes | Yes |
Dan | No | No | 0 | Isosulfan and fluorescein | No | 2.5 (ns) | Yes | Yes |
Braat | No | No | ns | Patent Blue | Yes (57%) | 1.7 (1 to 4) | Yes | Yes |
Bertoglio | No | No | ns | Vital Blue | No | 2.9 (1 to 3) | Yes | No |
Read | No | No | 0 | Isosulfan blue 1% | No | 2 (ns) | No | No |
Patten | No | No | 0 | Technetium and patent blue | No | 3.5 (0 to 11) | Yes | Yes |
Bertagnolli | No | Yes | 0 | Isosulfan blue 1% | No | 2.1 (ns) | Yes | No |
Saha | No | No | 0 | Technetium and Isosulfan blue | No | 3 (1 to 4) | Yes | Yes |
Saha | No | Yes | 0 | Isosulfan, Technetium and fluorescein | No | 2 (1 to 4) | Yes | Yes |
Bembenek | No | No | 0 | Patent Blue | No | 2 (ns) | Yes | Yes |
Codnignola | No | No | 0 | Patent Blue | No | 2.02 (ns) | Yes | Yes |
Dahl | No | No | 0 | Patent Blue (with radioisotope in six) | Yes (6%) | 2.2 (0 to 6) | Yes | No |
Bilchik | Yes | Yes | 15 | Isosulfan blue 1% | Yes (4%) | 3 (ns) | Yes | Yes |
Tuech | Yes | No | ns | Patent Blue | Yes | 1.5 (ns) | Yes | Yes |
Saha | Yes | Yes | ns | Isosulfan blue 1% | No | 2.2 (ns) | Yes | yes |
Kelder | No | No | 0 | Patent Blue | No | 2.7 (1 to 4) | Yes | Yes |
Thomas | No | No | 0 | Isosulfan blue 1% | No | 2.1 (1 to 5) | Yes | yes |
Covarelli | No | No | 0 | Technetium and blue dye | No | 1.3 (ns) | Yes | Yes |
Kelder | Yes | Yes | 0 | Patent Blue | No | 2,3 (ns) | Yes | Yes |
Bianchi | No | No | 100 | Patent Blue | Yes (5%) | 2 (ns) | Yes | Yes |
Murawa | No | No | 0 | Patent Blue | No | 1.6 (0 to 4) | No | Yes |
Bembenek | No | Yes | 7 | Patent Blue | No | ns | Yes | Yes |
Sandrucci | No | No | ns | Patent blue and technetium | No | 2.2 (ns) | Yes | No |
Tiffet | No | No | 0 | Patent blue and technetium | No | 2.6 (ns) | Yes | Yes |
Lim | No | No | ns | Technetium and Isosulfan blue | Yes | 4 (ns) | Yes | Yes |
Kusano | No | No | 62% | Indocyanine green | No | 2.6 (0–5) | No | No |
Quadros | No | No | 0 | Technetium and patent blue | Yes | 3.5 (ns) | Yes | Yes |