Table 4 Risk factors associated with cancer-specific survival

Age (years)

< 60 vs. ≥ 60

1.1(0.4 − 2.7)

0.8

NA

Gender

Male vs. female

1 (0.3 − 2.9)

0.9

NA

Tumor location

Upper, mid vs. low

2.3 (0.9 − 5.6)

0.1

NA

Operation type

LAR vs. APE or Hartmann

1 (0.3 − 3)

1

NA

Duration (preoperative CRT to surgery)(week)

<6 vs. ≥6

0.5 (0.2 − 1.4)

0.6

NA

Tumor diameter (cm)

<3 vs. ≥3

1.9 (0.8 − 4.5)

0.2

NA

ypTNM

pCR,I vs. II,III,IV

11 (1.5 − 85)

0.02

10 (1.3 − 75)

0.03

CEA (ng/mL)

< 5 vs. ≥ 5

3.3 (1.4 − 8.2)

0.01

1.8 (0.7 − 4.7)

0.2

NLR

< 3 vs. ≥ 3

10 (2–49)

0.01

6.6 (1.3 − 32)

0.02