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Table 1 Clinicopathologic characteristics (n = 102)

From: Neutrophil-lymphocyte ratio predicts pathologic tumor response and survival after preoperative chemoradiation for rectal cancer

 

Pathologic response*

 
 

Good

Poor

 

Variable

N (%)

N (%)

P

Age (years)

<60

17 (48.6)

36 (53.7)

0.6

≥60

18 (51.4)

31 (46.3)

 

Gender

Male

28 (80)

54 (80.6)

0.9

Female

7 (20)

13 (19.4)

 

Tumor location

Upper (10.1-15 cm)

0 (0)

3 (4.5)

0.2

Mid (5.1-10 cm)

12 (34.3)

31 (46.3)

 

Low (<5 cm)

23 (65.7)

33 (49.3)

 

Operation type

Low anterior resection

30 (85.7)

56 (83.6)

0.8

APE or Hartmann procedure

5 (14.3)

11 (16.4)

 

Duration (preoperative CRT to surgery) (week)

<6

22 (62.9)

42 (62.7)

0.99

≥6

13 (37.1)

25 (37.3)

 

Tumor diameter (cm)

<3

30 (85.7)

38 (56.7)

0.003

≥3

5 (14.3)

29 (43.3)

 

ypT classification

0

9 (25.7)

4 (6.0)

<0.001

1

5 (14.3)

1 (1.5)

 

2

21 (60.0)

4 (6.0)

 

3

0 (0)

55 (82.1)

 

4

0 (0)

3 (4.5)

 

ypN classification

0

35 (100)

36 (53.7)

<0.001

1

0 (0)

22 (32.8)

 

2

0 (0)

9 (13.4)

 

CEA (ng/mL)

<5

29 (85.3)

35 (55.6)

0.003

 

≥5

5 (14.7)

28 (44.4)

 
  1. *Good response group: pathologic complete response and ypTNM I, poor response group: ypTNM II, III and IV.
  2. APE, abdominoperineal excision; CRT, chemoradiation; CEA, carcinoembryonic antigen.