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Table 3 Comparison between group A1 (<50 years, MMR-, thus HNPCC cases) and group B (> 50 years)

From: Lynch Syndrome from a surgeon perspective: retrospective study of clinical impact of mismatch repair protein expression analysis in colorectal cancer patients less than 50 years old

 

Group A1 (16)

Group B (85)

Group A2 (33)

P

Age (mean)

40

66

 

0.001

Symptoms

100%

62%

 

0.031

Extended surgery*

43.7%***

9,4%

 

0.032

Proximal localization**

43,7%

34,1%

 

0.46

Mucinous

56.2%

14,1%

 

0.047

Advanced stage (T3-4)

75%

36,4%

 

0.0042

Undifferentiated

31,2%

9,4%

 

0.0167

Disease free survival (mean)

63,9 m

81 m

 

0.057

Overall survival (mean)

64,5 m

89 m

 

0.048

Disease free survival (mean)

63,9 m

 

78,2 m

0.061

Overall survival (mean)

64,5 m

 

81,6 m

0.049

  1. *More than 1 segment colonic resection.
  2. **Proximal to the transverse colon, included.
  3. ***Including resections for metachronous tumors.
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BMC Surgery

ISSN: 1471-2482

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