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Table 2 Deficiency of mismatch repair protein expression (group A1)

From: Lynch Syndrome from a surgeon perspective: retrospective study of clinical impact of mismatch repair protein expression analysis in colorectal cancer patients less than 50 years old

Case

MLH1

MSH2

MSH6

AMST

BETH

Other tumors*

Familial history**

Colon recurrence

1

-

+

-

YES

YES

NO

YES

YES

2

-

+

+

NO

YES

YES

YES

YES

3

+

-

+

NO

YES

NO

NO

NO

4

+

+

-

NO

YES

YES

YES

NO

5

+

+

-

NO

YES

YES

NO

NO

6

-

+

+/-

NO

YES

NO

YES

YES

7

+

-

+

YES

YES

NO

NO

NO

8

-

+/-

+

NO

YES

NO

YES

NO

9

+

+

+/-

NO

YES

YES

YES

NO

10

+/-

+

+/-

YES

YES

NO

NO

NO

11

+

+

+/-

NO

YES

YES

YES

YES

12

+/-

+

+/-

YES

YES

NO

NO

NO

13

+/-

+

+

NO

YES

YES

YES

YES

14

+

+

+/-

NO

YES

YES

YES

YES

15

+

+

+/-

NO

YES

YES

YES

NO

16

+

+

+/-

YES

YES

NO

YES

NO

  1. +/- Partial expression of the protein.
  2. *Both synchronous and metachronous.
  3. **Four generations have been analyzed (see the text).