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Table 4 Proportion of patients (%) with important biochemical variables below or above reference value prior to, and at 12 and 24 months after laparoscopic sleeve gastrectomy

From: Changes in obesity-related diseases and biochemical variables after laparoscopic sleeve gastrectomy: a two-year follow-up study

Variable

Preoperative

12 months

24 months

P value

    

12 vs. 0 months

24 vs. 0 months

24 vs. 12 months

No. with available data/total no:

95-117/117

98-107/117

65-95/117

   
 

No. below or above reference/no with available data (%)

   

Hb<ref. (11,5-16,0 g/dl)

7/117 (6%)

5/105 (4.8%)

4/95 (4.2%)

1

1

1

Ferritin<ref. (25-300 ug/l)

13/116 (11.2%)

20/101 (19.8%)

28/85 (32.9%)

0.021

0.001

0.118

Folic acid<ref. (> 5 nmol/l)

8/106 (7.5%)

8/100 (8.0%)

2/91 (2.2%)

1

0.453

0.125

Cobalamin<ref. (145–540 pmol/l)

4/111 (3.6%)

7/107 (6.5%)

3/94 (3.2%)

0.508

1

0.727

25(OH)D<ref. (30-150 nmol/l)

29/110 (26.4%)

5/105 (4.8%)

8/79 (10.1%)

<0.001

<0.001

0.289

25(OH)D<50 nmol/l)

73/110 (66.4%)

39/105 (37.1%)

24/79 (30.4%)

<0.001

<0.001

0.839

1,25(OH)2D>ref. (50-145 pmol/l)

0/104 (0.0%)

3/98 (3.1%)

1/65 (1.5%)

0.250

1

1

ALP>ref. (< 105 U/l)

6/116 (5.2%)

5/107 (4.7%)

7/94 (7.4%)

1

1

0.688

PTH>ref. (1.6-7.0 pmol/l)

35/95 (36.8%)

42/105 (40.0%)

36/85 (42.4%)

0.719

0.571

0.664

Calcium<ref. (2.15 – 2.55 mmol/l)

6/117 (5.1%)

1/108 (0.9%)

1/93 (1.1%)

0.124

0.125

1

Albumin<ref. (35-50 g/l)

16/117 (13.7%)

4/107 (3.7%)

8/94 (8.5%)

0.008

0.180

0.453

ALT>ref (35 U/l)

50/117 (42.7%)

11/107 (10.3%)

11/93 (11.8%)

<0.001

<0.001

1

  1. No = Number. Hb = Hemoglobin. Ref = Reference value. 25(OH)D = 25 hydroxyvitamin D. 1,25(OH)2D = 1,25 dihydroxyvitamin D. ALP = Alkaline Phosphatase. PTH = Parathyroid hormone. ALT = Alanine aminotransferase.