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Table 3 Proportion of patients (%) with obesity-related diseases prior to, and at 12 and 24 months after laparoscopic sleeve gastrectomy

From: Changes in obesity-related diseases and biochemical variables after laparoscopic sleeve gastrectomy: a two-year follow-up study

Variable

Preoperative

12 months

24 months

P value

    

12 vs 0 months

24 vs 0 months

24 vs 12 months

No. with available data/total no.

117/117

116/117

109/117

   

BMI (kg/m2, mean ± SD)

46.6 ± 6.0

30.3 ± 5.9

30.6 ± 5.6

<0.001

<0.001

0.936

Treated for

No. with disease/no. with available data (%)

   

T2DM

23/117 (19.7%)

5/114 (4.4%)

4/105 (3.8%)

<0.001

<0.001

1

Hypertension

50/117 (42.7%)

17/111 (15.3%)

16/104 (15.4%)

<0.001

<0.001

1

Hyperlipidemia

14/117 (12.0%)

5/114 (4.4%)

3/104 (2.9%)

0.039

0.021

1

Sleep apnea

15/117 (12.8%)

3/116 (2.9%)

1/109 (0.9%)

<0.001

<0.001

0.5

Obstructive lung disease

19/117 (16.2%)

19/114 (16.7%)

13/105 (12.4%)

1

0.063

0.063

Musculoskeletal pain

41/115 (35.7%)

29/114 (25.4%)

26/106 (24.5%)

0.067

0.026

0.804

Anxiety

18/117 (15.4%)

13/113 (11.5%)

11/103 (10.7%)

0.219

0.375

1

Depression

25/117 (21.4%)

18/113 (15.9%)

15/103 (14.6%)

0.109

0.125

1

GERD

15/117 (12.8%)

34/112 (30.4%)

29/106 (27.4%)

0.001

0.011

0.629

Suffering from (treated or not)

      

Snoring

89/114 (78.1%)

28/112 (25%)

13/102 (12.8%)

<0.001

<0.001

0.002

Premenopausal/total no. of women

71/87

67/87

63/87

   

Urinary leakage

33/87 (37.9%)

11/84 (13.1%)

8/79 (10.1%)

<0.001

<0.001

0.453

Amenorrhea

12/70 (17.1%)

3/65 (4.6%)

0/51 (0%)

0.021

0.016

1

Infertility

12/70 (17.1%)

*

4/52 (7.7%)

 

0.180

 
  1. BMI = Body mass index. SD = Standard deviation. No = Number. T2DM = Type 2 diabetes mellitus. GERD = Gastroesophageal reflux disease.
  2. *Pregnancy was strongly discouraged during the first 12 months. At 24 months, two of the 12 women defined as infertile preoperatively had given birth to two healthy children.