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Table 3 Proportion of patients (%) with obesity-related diseases prior to, and at 12 and 24 months after laparoscopic sleeve gastrectomy

From: Changes in obesity-related diseases and biochemical variables after laparoscopic sleeve gastrectomy: a two-year follow-up study

Variable Preoperative 12 months 24 months P value
     12 vs 0 months 24 vs 0 months 24 vs 12 months
No. with available data/total no. 117/117 116/117 109/117    
BMI (kg/m2, mean ± SD) 46.6 ± 6.0 30.3 ± 5.9 30.6 ± 5.6 <0.001 <0.001 0.936
Treated for No. with disease/no. with available data (%)    
T2DM 23/117 (19.7%) 5/114 (4.4%) 4/105 (3.8%) <0.001 <0.001 1
Hypertension 50/117 (42.7%) 17/111 (15.3%) 16/104 (15.4%) <0.001 <0.001 1
Hyperlipidemia 14/117 (12.0%) 5/114 (4.4%) 3/104 (2.9%) 0.039 0.021 1
Sleep apnea 15/117 (12.8%) 3/116 (2.9%) 1/109 (0.9%) <0.001 <0.001 0.5
Obstructive lung disease 19/117 (16.2%) 19/114 (16.7%) 13/105 (12.4%) 1 0.063 0.063
Musculoskeletal pain 41/115 (35.7%) 29/114 (25.4%) 26/106 (24.5%) 0.067 0.026 0.804
Anxiety 18/117 (15.4%) 13/113 (11.5%) 11/103 (10.7%) 0.219 0.375 1
Depression 25/117 (21.4%) 18/113 (15.9%) 15/103 (14.6%) 0.109 0.125 1
GERD 15/117 (12.8%) 34/112 (30.4%) 29/106 (27.4%) 0.001 0.011 0.629
Suffering from (treated or not)       
Snoring 89/114 (78.1%) 28/112 (25%) 13/102 (12.8%) <0.001 <0.001 0.002
Premenopausal/total no. of women 71/87 67/87 63/87    
Urinary leakage 33/87 (37.9%) 11/84 (13.1%) 8/79 (10.1%) <0.001 <0.001 0.453
Amenorrhea 12/70 (17.1%) 3/65 (4.6%) 0/51 (0%) 0.021 0.016 1
Infertility 12/70 (17.1%) * 4/52 (7.7%)   0.180  
  1. BMI = Body mass index. SD = Standard deviation. No = Number. T2DM = Type 2 diabetes mellitus. GERD = Gastroesophageal reflux disease.
  2. *Pregnancy was strongly discouraged during the first 12 months. At 24 months, two of the 12 women defined as infertile preoperatively had given birth to two healthy children.