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Table 1 Demographics, symptoms, and preoperative or postoperative biochemistry

From: Total parathyroidectomy with trace amounts of parathyroid tissue autotransplantation as the treatment of choice for secondary hyperparathyroidism: a single-center experience

Parameter

tPTX+AT Group (n=14)

tPTX Group (n=33)

P Value

Age, median (years)

46.5±13.9 (28–63)

45.8±14.2 (29–71)

>0.05

Men/women

8/6

18/15

>0.05

Duration of dialysis (years)

9 (3–19)

8.8 (3–17)

>0.05

Renal transplant (no.)

2

5

>0.05

Follow-up, mean (months)

43.1 ±8.9 (9–62)

41.6±10.4 (9–62)

>0.05

Preoperative BMD (Z-score)

-3.72±1.12

-3.66±0.98

>0.05

Symptoms

   

Fractures or bone pain (no.%)

14 (100)

33 (100)

>0.05

Kidney stone (no.%)

0

0

 

Pruritus (no.%)

12 (85.7)

30 (90.9)

>0.05

Fatigue/weakness (no.%)

8 (57.1)

20 (60.6)

>0.05

Osteoporosis (no.%)

13 (92.8)

32 (96.9)

>0.05

Preoperative biochemistry

   

PTH (ng/L)

2746 ± 886 (2430–3809)

2798 ±983 (1600–4280)

>0.05

Ca (mmol/L)

2.6 ±0.21 (2.28-2.81)

2.58 ±0.23 (2.3-2.95)

>0.05

P (mmol/L)

2.5 ±0.73 (1.75-3.91)

2.52 ±0.82 (1.77-4.31)

>0.05

25(OH)D3(ng/ml)

10.31±2.35

10.45±2.41

>0.05

Postoperative 1st day biochemistry

 

(n=31)

 

PTH (ng/L)

35.3±16.8

16.8±7.5

>0.01

Ca (mmol/L)

1.92 ±0.38

1.79±0.37

>0.05

P (mmol/L)

1.83±0.71

1.76±0.68

>0.05

Symptoms relief (no.%)

 

(n=31)

 

Bone pain (no.%)

14 (100)

31 (100)

<0.05

Pruritus (no.%)

12 (100)

30 (96.8)

>0.05

Postperative BMD (Z-score)

-2.83±1.92

-3.16±1.68

>0.05

Recurrence

0

0

<0.05

Postoperative symptomatic recurrent hypocalcemia

0

2

<0.05

Postoperative 6 months biochemistry

 

(n=31)

 

PTH (ng/L)

13.69±6.29

8.87±6.15

<0.05

Ca (mmol/L)

2.01±0.19

1.91±0.21

<0.05

P (mmol/L)

0.895±0.18

0.95±0.22

<0.05

25(OH)D3 (ng/ml)

16.36±2.67

11.71±2.34

<0.05

  1. Abbreviations: tPTX+AT total parathyroidectomy with autotransplantation, tPTX total parathyroidectomy, BMD bone mineral density, PTH parathyroid hormone, 25(OH)D3 25-Hydroxyvitamin D3.