Parameter | tPTX+AT Group (n=14) | tPTX Group (n=33) | P Value |
---|---|---|---|
Age, median (years) | 46.5±13.9 (28–63) | 45.8±14.2 (29–71) | >0.05 |
Men/women | 8/6 | 18/15 | >0.05 |
Duration of dialysis (years) | 9 (3–19) | 8.8 (3–17) | >0.05 |
Renal transplant (no.) | 2 | 5 | >0.05 |
Follow-up, mean (months) | 43.1 ±8.9 (9–62) | 41.6±10.4 (9–62) | >0.05 |
Preoperative BMD (Z-score) | -3.72±1.12 | -3.66±0.98 | >0.05 |
Symptoms | |||
Fractures or bone pain (no.%) | 14 (100) | 33 (100) | >0.05 |
Kidney stone (no.%) | 0 | 0 | |
Pruritus (no.%) | 12 (85.7) | 30 (90.9) | >0.05 |
Fatigue/weakness (no.%) | 8 (57.1) | 20 (60.6) | >0.05 |
Osteoporosis (no.%) | 13 (92.8) | 32 (96.9) | >0.05 |
Preoperative biochemistry | |||
PTH (ng/L) | 2746 ± 886 (2430–3809) | 2798 ±983 (1600–4280) | >0.05 |
Ca (mmol/L) | 2.6 ±0.21 (2.28-2.81) | 2.58 ±0.23 (2.3-2.95) | >0.05 |
P (mmol/L) | 2.5 ±0.73 (1.75-3.91) | 2.52 ±0.82 (1.77-4.31) | >0.05 |
25(OH)D3(ng/ml) | 10.31±2.35 | 10.45±2.41 | >0.05 |
Postoperative 1st day biochemistry | (n=31) | ||
PTH (ng/L) | 35.3±16.8 | 16.8±7.5 | >0.01 |
Ca (mmol/L) | 1.92 ±0.38 | 1.79±0.37 | >0.05 |
P (mmol/L) | 1.83±0.71 | 1.76±0.68 | >0.05 |
Symptoms relief (no.%) | (n=31) | ||
Bone pain (no.%) | 14 (100) | 31 (100) | <0.05 |
Pruritus (no.%) | 12 (100) | 30 (96.8) | >0.05 |
Postperative BMD (Z-score) | -2.83±1.92 | -3.16±1.68 | >0.05 |
Recurrence | 0 | 0 | <0.05 |
Postoperative symptomatic recurrent hypocalcemia | 0 | 2 | <0.05 |
Postoperative 6 months biochemistry | (n=31) | ||
PTH (ng/L) | 13.69±6.29 | 8.87±6.15 | <0.05 |
Ca (mmol/L) | 2.01±0.19 | 1.91±0.21 | <0.05 |
P (mmol/L) | 0.895±0.18 | 0.95±0.22 | <0.05 |
25(OH)D3 (ng/ml) | 16.36±2.67 | 11.71±2.34 | <0.05 |