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Table 8 Other surgery types

From: Use of Floseal®, a human gelatine-thrombin matrix sealant, in surgery: a systematic review

Surgery type Author and year Comparator and patients per arm (n) Primary endpoint Principal results
Gynaecologic surgery Angioli 2009[23] Floseal® (8) Control of minor bleeding Not significant differences in the time to haemostasis, blood loss, or the operating time.
Control (bipolar forceps or carbon-dioxide laser) (12)
Raga 2009[24] Floseal® (25) Haemostatic efficacy Less intra- and postoperative blood loss (p = 0.001) and a lower rate of transfusions (0% in the Floseal® group) (p < 0.001) for patients treated with Floseal®. A shorter length of hospital stay in the Floseal® group (p = 0.005).
Isotonic sodium chloride (25)
Sönmezer 2013[25] Floseal® (13) Ovarian reserve and damage During the first postoperative month, ovarian damage was significantly lower in the Floseal® group (p < 0.001). However, at the third month after surgery, NS differences were found.
Bipolar electrosurgical coagulation (15)
Lacrimal surgery Durrani 2007 Floseal® (10) Postoperative bleeding and patient comfort Nine patients in the Floseal® group had no or minimal bleeding; this finding was statistically significant at all three measured time points (immediately (p = 0.047), at 12 h (p = 0.006), and at 24 h after surgery (p = 0.005)). The Floseal® group also had less postoperative discomfort (p = 0.0001). 
Without Floseal® (10)
Thyroid surgery Testini 2009[22] Floseal® (54) Operating time and wound drain removal A significantly shorter operating time in the Floseal® group than in the other groups (p < 0.05). More rapid wound drain removal and a shorter length of hospital stay in the Floseal® group compared with the other groups (p < 0.05 both). Not significant difference in postoperative morbidity.
Surgical haemostasis (49)
Tabotamp (52)