Table 6 Tonsillectomy and adenoidectomy
From: Use of Floseal®, a human gelatine-thrombin matrix sealant, in surgery: a systematic review
Author and year | Comparator and patients per arm (n) | Primary endpoint | Principal results |
|---|---|---|---|
Jo 2007[15] | Floseal® (34) | Postoperative recovery time and morbidity | Floseal® decreased postoperative pain and narcotic pain medication use (p < 0.05 both) and resulted in a faster return to regular diet and activity (p < 0.01 both). Also shorter operative times were observed (p < 0.0001) and less blotod loss (p < 0.05) with Floseal® |
Electrocautery (34) | |||
Blackmore 2008[12] | Ligatures (one fossa randomised to Floseal® and the other to ligatures) (30) | Postoperative pain | No reduction in pain in the Floseal® group. |
Mathiasen 2004[14] | Floseal® (35) | Time to haemostasis and blood loss | Floseal® yielded significantly shorter times to haemostasis and less blood loss (p < 0.0001 both). |
Cautery (35) | |||
Mozet 2012[13] | Floseal® (89) | Handling, duration, and consumption of postoperative pain medication; wound healing; and rate of postoperative haemorrhage | The Floseal® group had less postoperative pain (p = 0.074), a significantly shorter duration of pain medication use (p = 0.014), and reduced pain medication consumption/demand (p = 0.032). Not significant difference in postoperative haemorrhage. |
Bipolar electrocautery (87) |