Table 3 Comparison of clinical characteristics of patients in whom factor XIII concentrate was effective for persistent air leak and those in whom it was ineffective

Sex (Male/Female)

21/5

9/2

0.941

Age

68 (61–72)

72 (69–77)

0.018

BMI

21.4 (19.9–24.9)

18.7 (18.0–19.4)

<0.001

Smoking Index

950 (600–1783)

940 (600–1400)

  Ever-smoker/Never

22/4

10/1

0.609

Diabetes (Yes/No)

6/20

3/8

0.786

FEV1.0%

71.1 (59.6–77.2)

70.0 (64.9–83)

0.561

DLCO%

84.4 (72.4–104.1)

82.3 (68.6–99.9)

0.698

COPD/IP (Yes/ No)

15/11

9/2

0.160

Operative procedure (upper or bilobectomy/other)

17/9

6/5

0.534

Pleural Adhesion (major/minor or no)

6/20

1/10

0.321

Repair air leak during operation

  No

3

0

0.137

  PGA sheet or suture

3

4

  Both PGA and suture

20

7

Fibrin glue during operation (Yes/No)

25/1

10/1

0.519

Air leak at first postoperative day

  Forced expiratory only

8

5

0.276

  Expiratory only

12

2

  Continuous

6

4

Duration of air leak (days)

7 (6–9)

15 (10–19)

<0.001

Duration of drainage (days)

8 (7–11)

17 (15–22)

<0.001

Drainage amount of 5 days (ml)

1220 (1050–1543)

1054 (626–1554)

0.291

  Plasma factor XIII activity (%)

  Before operation

110 (89–130)

123 (99–147)

0.394

  Postoperative day 5

74 (64–86)

91 (77–125)

0.030

  Decrease ratio (%)

24 (7–39)

14 (1–36)

0.393