Table 3 Overview of surgical complications: comparison of neoadjuvant R(C)T with and without intensification to our results
From: Intensified neoadjuvant radiochemotherapy for rectal cancer enhances surgical complications
| Â | Subject | 30Â day mortality (%) | Anastomotic leakage (%) | Operative revision of anastomotic leakage (%) | Perineal wound infection (%) |
|---|---|---|---|---|---|
Own results (n = 212) | +/- intensified RCT | 0 / 1.9 | 26.6 / 9.7 | 20.3 / 6.5 | 42.2 / 18.8 |
Sauer et al. [1] (n = 823) | Pre/post-operative RCT | 0.7 / 1.3 | 11 / 12 |  | 10 / 8+ |
Bosset et al. [20] (n = 1011) | RT/RCT | 1.2 / 2.4 |  |  |  |
Kapiteijn et al. [19] (n = 1861) | +/- RT | No difference | No difference |  | 26 / 18 |
Voelter et al. [8] (n = 33) | Intensified RCT | 3 | 6 |  | 58 |
Horisberger et al. [21] (n = 59) | All patients / major/minor response to intensified RCT | 3.4 | 15.5 | 15.5 |  |
6.1 / 0 | 25.9 / 0 | 25.9 /0 | |||
Gollins et al. [14] (n = 46) | Intensified RCT | 0 | 6.4 |  | 22.2§ |
Aschele et al. [22] (n = 747) | Intensified (Oxaliplatin)/"not intensified" RCT | 1 / 1 | 2 / 1 |  | 9 / 9& |
Sato et al. [23] (n = 67) | S-1 plus Irinotecan | 0 | 0 | 0 | 0 |
Garlipp et al. [24] (n = 2085) | +/- preoperative chemoradio-therapy |  | 12.4 / 12.7 | 5.5 / 7.5 |  |
Fucini et al. [25] (n = 80) | +/- preoperative RCT | 2 / 0 | 14.8 / 9.1 |  |  |