Intensified neoadjuvant radiochemotherapy for rectal cancer enhances surgical complications

BMC Surgery

Table 2 Postoperative morbidity stratified by intensified neoadjuvant radiochemotherapy

	With neoadjuvant treatment% (n = 106)	Without neoadjuvant treatment% (n = 106)	p-value
30 day mortality	0.0	1.9	0.244
Complications	53.8	50.5	0.550
Non surgical	11.3	23.1	0.028
Urinary infection	2.8	9.6	0.048
Pneumonia	3.8	6.7	0.371
Cardiopulmonary events	0.9	4.8	0.117
Surgical	50.0	31.7	0.018
Wound infections (any grade)	20.8	9.6	0.034
Perineal wound infections (rectum exstirpation only)	42.2	18.8	0.032
Anastomosis leakage (LAR only)	26.6	9.7	0.020
Operative revision (LAR only)	20.3	6.5	0.035

After administrating intensified neoadjuvant treatment, there is no increase in non surgical morbidity, but a severe increase in surgical morbidity like anastomosis leakage or wound infections.

ISSN: 1471-2482