Intensified neoadjuvant radiochemotherapy for rectal cancer enhances surgical complications

BMC Surgery

Table 1 Patient and cancer characteristics for patients with vs. without intensified neoadjuvant RCT

	With neoadjuvant treatment% (n = 106)	Without neoadjuvant treatment% (n = 106)	p-value
Patients:	50	50
Gender ratio (f : m)	1 : 2.92	1 : 1.35	0.01
Age	62.3	68.5	0.067
Comorbidity	68.6	84.6	0.009
Pulmonary	5.7	14.4	0.041
Cardiovascular	21.9	25.0	0.627
Renal	6.7	11.5	0.239
Diabetes	11.4	19.2	0.128
Hypertension	40.0	56.7	0.019
Others	39.0	62.5	0.001
ASA score (mean)	2.28	2.38	0.228
BMI (mean)	26.4	25.9	0.500
Diverting stoma (continous resections only)	76.6	71.0	0.545
Discontinous resection	38.7	40.6	0.888
Rectum exstirpation	29.2	30.2	1.000
Preexisting fecal insuffiency (discontinous resections only)	8.7	17.4	0.665
Infiltration of anal sphincter (discontinous resections only)	54.2	47.8	0.773
Close distance to anal sphincter (discontinous resections only)	43.5	31.8	0.542
Infiltration (pT)			0.026
ypT0	8.5	0.0
(y)pT1	5.7	10.4
(y)pT2	27.4	33.0
(y)pT3	54.7	52.8
(y)pT4	3.8	3.8
Lymph node metastasis (pN)			0.945
(y)pN0	52.8	53.3
(y)pN1	27.4	28.6
(y)pN2	19.8	18.1
Number of nodes examined	15.3	18.8	0.001
UICC stage			0.116
UICC 0	3.8	0.0
UICC I	24.5	32.1
UICC II	17.0	17.0
UICC III	31.1	35.8
UICC IV	23.6	15.1
Localization			0.986
Upper Rectum	3.8	3.8
Middle Rectum	40.4	41.5
Lower rectum	55.8	54.7
Tumorheight (cm)	5.26	5.31	0.199

Patient characteristics were recorded within three days before surgery, tumor heights was documented at the time of staging and cancer characteristics were taken from the pathological report.

ISSN: 1471-2482