Parameters | Â | Â | Timepoints | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SEH | Surgical procedure | Postoperative days | ||||||||||||||
 | Anesthesia | 30 minutes after intervention | Pre-anhepatic phase | Anhepatic phase | Reperfusion phase | 0/1 | 2 | 3 | 4 | 5 | 6 | 7 | 11 | 14 | 30 | |
12-leads ECG | x | According to local protocol | Â | Â | x | Â | Â | Â | x | Â | Â | Â | ||||
Lab | x | x | x | x | x | x | x | x | Â | x | x | |||||
Troponin | x | x | Â | Â | Â | Â | Â | Â | Â | Â | Â | |||||
Plasma sample | x | x | x | 1Â hour after intervention | 15Â minutes after start phase | 15Â minutes after start phase | x | Â | x | Â | x | Â | Â | x | Â | Â |
2Â hours after intervention | end of surgery | |||||||||||||||
Viral safety | x | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
TEG/ROTEM | Â | Â | Â | Â | 15Â minutes after start phase | 30Â minutes after start phase | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Blinded INR | Â | Â | x | Â | Â | Â | x | Â | x | Â | Â | Â | x | Â | Â | Â |
Ultrasound hepatic vessels | Â | According to local protocol | Â | Â | Â | Â | first 24Â h after surgery | Â | Â | Â | Â | Â | ||||
Registration transfusion products | Â | Â | x | x | x | x | Â | Â | x | Â | Â | Â | x | Â | Â | Â |
Physical examination with focus on thrombotic and ischemic events | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |