Skip to main content

Table 4 Univariate and multivariate regression analysis for DFS and OS in the whole cohort

From: Overexpression of Cystatin SN positively affects survival of patients with surgically resected esophageal squamous cell carcinoma

Variables

Disease-free survival

Overall survival

 

Univariate analysis

Multivariate analysis

Univariate analysis

Multivariate analysis

 

HR

95% CI

P value*

HR

95% CI

P value*

HR

95% CI

P value*

HR

95% CI

P value*

Age†

1.258

0.872-1.813

0.219

.....

.....

.....

1.359

0.933-1.981

0.110

.....

.....

.....

Gender‡

0.832

0.535-1.295

0.416

.....

.....

.....

0.759

0.478-1.205

0.242

.....

.....

.....

Location§

0.763

0.558-1.043

0.090

.....

.....

.....

0.751

0.542-1.040

0.084

.....

.....

.....

Surgery¶

1.034

0.851-1.256

0.738

.....

.....

.....

1.052

0.863-1.284

0.615

.....

.....

.....

pT status¿

1.133

0.782-1.644

0.509

.....

.....

.....

1.118

0.772-1.618

0.554

.....

.....

.....

Differentiation£

1.393

1.065-1.823

0.016

1.411

1.086-1.833

0.010

1.319

1.004-1.734

0.047

1.331

1.020-1.738

0.035

pN statusð

3.211

2.198-4.692

< 0.001

3.096

2.131-4.498

< 0.001

3.032

2.056-4.471

< 0.001

2.926

1.998-4.286

< 0.001

Cystatin SNζ

0.431

0.271-0.685

< 0.001

0.426

0.270-0.672

< 0.001

0.377

0.231-0.616

< 0.001

0.378

0.233-0.614

< 0.001

  1. *Cox proportional hazards model; †Age ≤ 57 vs. Age > 57; ‡Male vs. Female; §Upper thoracic vs. Middle thoracic vs. Lower thoracic; ¶Left thoracotomy vs. Thoracic-abdominal-cervical incision; ¿pT1 vs. pT2 vs. pT3 vs. pT4; £Tumor grade 1 vs. Tumor grade 2 vs. Tumor grade 3; ðpN0 vs. pN1/2/3; ζHigh expression of Cystatin SN vs. low expression of Cystatin SN. HR hazard ratio, CI confidence interval, pT pathologic tumor, pN pathologic node.