Skip to main content

Table 2 Effects of interventions sorted by comparison.

From: Topical haemostatic agents for skin wounds: a systematic review

Comparison Trial Haemostatic effect Healing Adverse effects Costs
1. Epinephrine vs. thrombin Brezel et al. 1987 + NS NS direct costs in favour of epinephrine
  Carucci et al. 1984 + no data NS probably favouring epinephrine
  Netscher et al. 1996 + no data NS direct costs in favour of epinephrine*
2. Epinephrine vs. control Carucci et al. 1984 + no data NS probably favouring control*
  Gacto et al. 2008 + favouring epinephrine NS no data
  Netscher et al. 1996 + no data NS probably favouring control*
  Barret et al. 1999 NS NS NS no data
3. Fibrin sealant vs. control Nervi et al. 2001 + no data no data no data
  Greenhalgh et al. 1999 +/NS/NS** NS NS no data
4. Fibrin sealant vs. thrombin Drake et al. 2003 + NS NS no data
5. Thrombin vs. control Carucci et al. 1984 + no data NS probably favouring control*
  Netscher et al. 1996 + no data NS probably favouring control*
6. Alginate dressing vs. fine mesh gauze Steenfos et al. 1998 + NS NS no data
  1. + = significantly in favour of the former agent;
  2. - = significantly in favour of the latter agent;
  3. NS = not significant.
  4. * Only direct costs per product or per patient were given, so no conclusion on overall costs per treatment could be conducted.
  5. ** Blood loss was estimated in three different ways.