Table 2 Definitions of isolated tumor cells (ITCs) and micrometastases (MMS)
Definitions used in EnRoute⊕ Study | ||
|---|---|---|
Isolated Tumor Cells (ITCs) | Micrometastases (MMs) | |
Size | < 0.2 mm | 0.2 - 2 mm |
Localization | No defining criterion | No defining criterion |
Detection method | HES and/or IHC | HES and/or IHC |
Formal designation (present vs absent) | pN0i+ vs pN0i- | pN0mi+ vs pN0mi- |
Designation for study purposes if present | pN0micro+ | pN0micro+ |