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Table 2 Australian and NZ studies reporting adverse events from surgery involving patients with colorectal cancer

From: Potential hospital cost-savings attributed to improvements in outcomes for colorectal cancer surgery following self-audit

Author, Year & No. cases % elective cases % anastomotic leak (AL) % wound infection % DVT % return to theatre % respiratory % 30-day deaths
Semmens 2000 [16] n = 9,673 77% 6.5% 8.3% post-op infect ns Most of AL (est.5%) ns 4.2%
Birks 2001 [15]
n = 877
69% 3.3% 7.2% ns 5.7% ns 4.1% CRC patients
Kable 2002 [17]
n = 5,432
ns ns 2.1% 0.3% ns pneumonia 0.2% 0.8%
Killingback 2002 [19] n = 1,418 100% 4.1% 2.1% 1.1% 2.7% 6.7% (incl various) 1.6%
McGrath 2004 [10, 11] & 2005
n = 1,911
86-93% 0.0-3.0% 6.6-9.1% 1.0-6.7% ns 0-1.6% pulmonary embolism 4.0-4.3%
Wong 2005 [30]
n = 1,293
83% 0.5-1.1% 4.2-7.8% 2.3-3.9% 2.7-6.7% ns 1.2-7.7%
Gollop 2006 [13]
n = 170
71% 3% Ns ns 12% ns 5%
Samson 2007 [14]
n = 191
ns 4.5% 11% ns 7% ns 4%
O'Grady 2007 [12]
n = 133
91% 4.7% 22% ns 3% 7.5% 0.8%
Bowles 2007 [4]
n = 500 pre
n = 100 post
63% Pre 8.2%
Post 1.4%
Ns ns Pre 12.2%
Post 5%
ns Pre 6.38%
Post 0%
Frye 2009 [18]
n = 1,513
100% 3.8% Ns ns ns ns 0.2%
SUMMARY1
low-high values
  0.5-8.2% 2.1-9.1% 0.3-6.7% 2.7-12.2% 0.2-10.7% 0.2-7.7%
  1. (Abbreviations: ns = not stated, DVT = deep vein thrombosis, AL = anastomotic leak, CRC = colorectal cancer)
  2. 1. Summary rates exclude 0% where reported and 22.3% wound infection rate from O'Grady 2007 that was considered an outlier and possibly due to inclusion of superficial and deep infections.