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Table 2 Outcome analysis

From: Selective decontamination of the gastrointestinal tract in patients undergoing esophageal resection

 

Group

p value

 

retrospective without SDD (n = 68)

retrospective with SDD (n = 53)

prospective with SDD (n = 81)

 

Mortality [30 days postoperative]

12 (17.6%)

(10.2% - 28.5%)

OR: 1 ref)

1 (1.9%) (0.0% - 10.9%)

OR: 0.09 (0.01-0.71)

1 (1.2%)

(0.0% - 7.3%)

OR: 0.06 (0.01-0.46)

<0.001 A)

Anastomotic

Leakage

9 (13.2%)

(6.9% - 23.5%)

OR: 1 ref)

2 (3.8%)

(0.3% - 13.5%)

OR: 0.26 (0.05 - 1.24)

6 (7.4%)

(3.2% - 15.5%)

OR: 0.52 (0.18-1.56)

0.162 A)

Postoperative

Pneumonia

17 (25.0%)

(16.2% - 36.5%)

OR: 1 ref)

6 (11.3%)

(4.9% - 22.9%)

OR: 0.38 (0.14-1.05)

4 (4.9%)

(1.6% - 12.4%)

OR: 0.16 (0.05-0.49)

0.001 A)

length of hospital stay [days]

25.2 ± 18.0

21.8 ± 13.7

20.2 ± 10.9

0.121 B)

  1. n (percentage) (95% CI for percentage) Odds ratio (95% CI for Odds ratio)
  2. A) Chi square tests for overall significance B) Kruskal Wallis tests for overall significance
  3. Closed testing procedure with chi square tests for: Mortality Leakage Pneumonia
  4. retrospective with SDD - retrospective without SDD p = 0.005 p = 0.072 p = 0.057
  5. prospective with SDD - retrospective without SDD p < 0.001 p = 0.239 p < 0.001
  6. retrospective with SDD - prospective with SDD p = 0.761 p = 0.385 p = 0.169