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Table 1 Analysis of clinicopathological factors for prognosis

From: Clinicopathological analysis of recurrence patterns and prognostic factors for survival after hepatectomy for colorectal liver metastasis

Factor

Number of patients

3-year survival rate (%)

5-year survival rate (%)

Univariate

P-value

Multivariate P-value

Sex

   

0.9217

 

Male

55

61.1

57.0

  

Female

28

65.9

58.6

  

Location of CRC

     

Rt-hemicolon

13

38.1

38.1

  

Transverse colon

9

75.0

56.3

  

Lt-hemicolon

38

58.8

53.9

  

Any colon

60

57.0

50.7

0.0794

 

Rectum

23

81.3

81.3

  

Depth of CRC

   

0.0133

0.3183

< ss (a1)

58

70.0

66.5

  

≥ se (a2)

23

47.3

39.4

  

Tumor differentiation of CRC

   

0.4712

 

Well

37

70.4

65.0

  

Moderate

41

53.3

48.0

  

Poor

1

100.0

100.0

  

Lymphatic invasion of CRC

   

0.7469

 

Present

66

62.6

62.6

  

Absent

14

73.5

45.9

  

Venous invasion of CRC

   

0.4259

 

Present

63

67.2

64.2

  

Absent

18

55.6

41.7

  

Lymph node metastasis of CRC

   

0.6040

 

0

30

70.9

57.8

  

1~3

39

64.0

64.0

  

≥4

13

48.4

48.4

  

Present

52

59.7

59.7

0.6779

 

Absent

30

70.9

57.8

  

Duke's stage of CRC

   

0.4376

 

A

7

80.0

80.0

  

B

11

60.6

22.7

  

C

33

60.2

60.2

  

D

30

65.0

65.0

  

Age at hepatectomy

   

0.5150

 

< 50 years

6

66.7

66.7

  

≥50 years

77

64.5

57.0

  

CEA before hepatectomy

   

0.2441

 

< 5 ng/ml

27

53.9

49.4

  

≥ 5 ng/ml

54

68.7

62.4

  

Time of liver metastasis

   

0.7865

 

Synchronous

28

61.2

61.2

  

Metachronous

55

63.7

56.8

  

Timing of hepatectomy

   

0.4927

 

Synchronous

13

70.5

70.5

  

Metachronous

70

61.5

55.2

  

Method of hepatectomy

   

0.4862

 

Anatomical

44

62.1

55.9

  

Non-anatomical

39

63.2

59.0

  

Extent of hepatectomy

   

0.0875

 

< Lobectomy

62

67.1

63.8

  

≥ Lobectomy

21

46.5

31.0

  

Number of CRCLM

   

0.3868

 

Solitary

47

69.3

61.0

  

Multiple

36

51.8

51.8

  

Location of CRCLM

   

0.1882

 

Unilobar

63

68.9

62.6

  

Bilobar

20

32.2

32.2

  

Size of CRCLM

   

0.9254

 

< 3 cm

42

71.3

62.9

  

3 - 5 cm

26

51.8

51.8

  

≥ 5 cm

14

50.4

50.4

  

Resection margin of CRCLM

   

0.0399

0.3917

< 5 mm

28

47.8

41.8

  

≥ 5 mm

49

70.4

64.5

  

Portal vein invasion of CRCLM

   

0.0074

0.2689

Present

8

28.6

0

  

Absent

74

66.2

63.4

  

Intrahepatic recurrence

   

0.0104

0.0051

Present

32

44.6

32.5

  

Absent

46

75.1

75.1

  

Extrahepatic recurrence

   

0.0217

0.0064

Present

26

43.1

43.1

  

Absent

54

69.4

63.0

  

Lung recurrence

   

0.1349

 

Present

18

39.9

-

  

Absent

62

66.1

60.3

  

Chemotherapy before hepatectomy

   

0.0991

 

Present

35

51.1

43.8

  

Absent

48

72.7

68.6

  

Chemotherapy after hepatectomy

   

0.3617

 

Present

56

63.6

60.3

  

Absent

22

52.8

45.2

  
  1. CRC: colorectal cancer, CRCLM: liver metastasis from colorectal cancer, CEA: carcinoembryonic antigen.