Inclusion criteria | Exclusion criteria |
---|---|
• Patients of both sexes undergoing a primary elective median abdominal incision | • Patients with a known history of adhesion or peritonitis |
• Age equal or greater than 18 years | • Patients with a known sensitivity to polyvinylalcohol or carboxy-methylcellulose |
• Written informed consent | • Simultaneous participation in another clinical trial with interfering end-points |
• Expected incison length ≥15 cm | • Emergency surgery |
• Expected survival time more than12 months | • Patients with peritoneal carcinosis or peritoneal dialysis |
• For female adults of reproductive potential: negative pregnancy test at visit 1 and sufficient contraception from time of written consent up to at least 4 months | • Patients with systemic immunsuppression (e.g. hydrocortisone >50 mg per daily, other immunsuppressants like Azathropin, Mycophenolatmofetil, Ciclosporin, Everolimus, Methotrexat ect.), chemotherapy or radiotherapy within the last 2 weeks prior surgery |
• Patients with ascites >200 ml | |
• ASA > 3 | |
• Patients with intra-abdominal abscess or other intra-abdominal infection | |
• Renal impairment (Creatinine >1.3 mg/ml) | |
• Pregnant or breast-feeding women | |
• Lack of compliance | |
• Surgical procedures or patients which require insertion more than 2 intra abdominal drains |