Energy expenditure related biomarkers following bariatric surgery: a prospective six-month cohort study

BMC Surgery

Table 4 Biochemical glycolipid profile at three time points before and after surgery

Variables^a	Before surgery	After Surgery		P-Value
Variables^a	Baseline	3 months	6 months	P-Value
PGC-1α, ng/ml	2.55 ± 0.04	2.78 ± 0.06	2.86 ± 0.23	0.01 ^b
UCP-2, ng/ml	5.13 ± 0.09	6.11 ± 0.16	8.11 ± 0.09	0.007 ^b
HOMA-IR	5.12 ± 0.44	2.84 ± 0.21	2.11 ± 0.23	0.001
FBS, mg/dL	109.64 ± 28.08	91.13 ± 13.87	89.53 ± 8.90	0.02
HbA1c, %	6.79 ± 0.72	5.80 ± 0.45	5.21 ± 0.39	0.03
Insulin, µIU/mL	18.07 ± 6.49	12.18 ± 4.15	9.85 ± 8.33	0.001
TG, mg/dL	163.36 ± 53.38	138.97 ± 41.46	129.81 ± 35.74	< 0.001
Chol, mg/dL	182.42 ± 40.35	168.06 ± 40.72	153.44 ± 34.98	< 0.001
LDL, mg/dL	108.61 ± 32.59	95.24 ± 28.17	86.58 ± 20.54	< 0.001
HDL, mg/dL	45.72 ± 11.86	45.00 ± 8.35	44.90 ± 2.81	0.84
ALT, IU/L	29.51 ± 12.80	23.19 ± 7.39	18.36 ± 3.97	< 0.001
AST, IU/L	31.03 ± 16.71	22.08 ± 9.21	16.08 ± 4.67	< 0.001

PGC-1α Peroxisome Proliferator Activated Receptor—Co-Activator-1a, UCP-2 Uncoupling protein 2, HOMA-IR Homeostatic model assessment-insulin resistance, FBS Fasting Blood Sugar, HbA1c Hemoglobin A1c, TG triglyceride, HDL high-density lipoprotein, LDL Low-density lipoprotein, AST Aspartate Transaminase, ALT alanine aminotransferase
^aMean ± SE
^bAdjusted for physical activity

ISSN: 1471-2482