Table 3 Univariate and multivariate analysis of predictors for major postoperative complications(Clavien-Dindo grade ≥ IIIb)

Age

1.14 (1.06–1.23)

 < 0.001

1.11 (1.02–1.21)

0.014

Sex (Female)

0.62 (0.28–1.49)

0.300

—

BMI

0.98 (0.87–1.10)

0.758

—

Preoperative TBIL

1.03 (0.93–1.14)

0.546

Preoperative bile drain

0.59 (0.25–1.40)

0.231

CCI

 0–1

Reference

—

 2–5

0.89 (0.33–2.42)

0.819

—

ASA physical status

 I-II

Reference

Reference

 III-V

8.48 (1.92–37.39)

0.004

4.56 (0.95–21.94)

0.058

GNRI score

—

 No risk

Reference

Reference

  Low risk

1.67 (0.45–6.24)

0.448

1.35 (0.33–5.57)

0.678

 High/moderate risk

5.88 (2.01–17.19)

0.001

3.61 (1.12–11.69)

0.032

  MIS approach^a

0.79 (0.27–2.29)

0.666

—

 Operative time

  Time < 8 h

Reference

Reference

 Time > 8 h

2.99 (1.26–7.09)

0.013

3.04 (1.14–8.13)

0.027

Operative blood loss

  < 400 ml

Reference

—

  > 400 ml

1.95 (0.82–4.63)

0.126

—

 Fistula Risk Score

1.14 (0.94–1.39)

0.192

—