From: Collagen patch cover facilitates recovery of bowel function after laparoscopic colectomy
Postoperative outcomes | Collagen group (n = 109) | Control group (n = 132) | p value |
---|---|---|---|
Number of days until first flatus | 2.9 ± 1 | 3.4 ± 1.5 | < 0.01 † |
Number of days until first oral intake | 3.7 ± 1 | 4.2 ± 1.7 | 0.01 † |
Number of days until first defecation | 4.3 ± 1.2 | 4.7 ± 1.7 | 0.04 † |
VAS | |||
Day 0 | 2.5 ± 0.7 | 2.4 ± 0.9 | 0.29 † |
Day 1 | 2 ± 0.7 | 1.9 ± 0.6 | 0.3 † |
Day 2 | 1.6 ± 0.6 | 1.7 ± 0.6 | 0.35 † |
Day 3 | 1.3 ± 0.6 | 1.5 ± 0.6 | 0.17 † |
Day 4 | 1.3 ± 0.6 | 1.3 ± 0.6 | 0.96 † |
Number of days of postoperative stay | 9.7 ± 3.7 | 10.5 ± 6.1 | 0.26 † |
Total amount of drainage, ml | 1095 ± 1519.3 | 1215.5 ± 1305 | 0.51 † |
Complication rate | 19 (17.4) | 18 (13.6) | 0.42 ‡ |
Paralytic ileus | 10 (9.2) | 10 (7.6) | 0.64 ‡ |
Surgical site infection | 6 (5.5) | 6 (4.5) | 0.72 ‡ |
Hemorrhage | 1 (1) | 4 (3.7) | 0.26 ‡ |
Anastomotic leakage | 1 (1) | 0 (0) | 0.27 ‡ |
Complication severity a | 0.99 ‡ | ||
Grade 1 | 2 (10.5) | 2 (11.1) | |
Grade 2 | 13 (68.4) | 12 (66.7) | |
≥ Grade 3 | 4 (21.1) | 4 (22.2) | |
BT | 0.489‡ | ||
≥ 38 °C | 35 (32) | 48 (36) | |
< 38 °C | 74 (68) | 84 (64) | |
WBC | 0.036‡ | ||
> 10,000/µL | 60 (55) | 90 (68) | |
≤ 10,000/µL | 49 (45) | 42 (32) | |
Dosage of IV analgesic | 3.4 ± 3 | 4.8 ± 5.8 | 0.02 † |
Types of analgesic | 0.12 | ||
No analgesic | 12 (11) | 21 (15.9) | |
NSAID | 34 (31.2) | 24 (18.2) | |
Opioids | 45 (41.3) | 62 (47) | |
NSAID + Opioids | 18 (16.5) | 25 (18.9) |